Domoic acid was identified as the toxin responsible for an outbreak of human poisoning that
occurred in Canada in 1987 following consumption of contaminated blue mussels [Mytilus …

In normal brain, neurons, astrocytes, and oligodendrocytes, the most abundant and active
cells express pannexins and connexins, protein subunits of two families forming membrane …

Human immunodeficiency virus (HIV)-1 infection of the CNS produces changes in dendritic
morphology that correlate with cognitive decline in patients with HIV-1 associated dementia …

N-methyl-d-aspartate receptors (NMDARs) are ion channels that respond to the
neurotransmitter glutamate, playing a crucial role in the permeability of calcium ions and …

Lead (Pb) toxicity is still a major health problem associated with both environmental and
occupational exposure. Special attention is given to the neurotoxic effect of lead. Along with …

For more than two decades the intensive research effort on the role of NMDA receptors
(NMDAR) in traumatic brain injury (TBI) and cerebral ischemia (stroke) was led by the …

Although traditionally associated with immune function, the transcription factor nuclear factor
kappa B (NF-κB) has garnered much attention in recent years as an important regulator of …

We report the preparation of gold nanoparticles (AuNPs) functionalized with the peptide-
toxin conantokin-G and their selective binding to N-methyl-d-aspartate (NMDA) receptors …

Glutamate plays a pivotal role in drug addiction, and the N-methyl-d-aspartate (NMDA)
glutamate receptor subtype serves as a molecular target for several drugs of abuse. In this …

Aims: Overactivation of glutamate N-methyl-D-aspartate receptor (NMDAR) increases the
cytosolic concentrations of calcium and zinc, which significantly contributes to neural death …