Strategies for unlocking immunosuppression in the tumor microenvironment have been
investigated to overcome resistance to first-generation immune checkpoint blockade with …

Simple Summary Internationally, in women, breast cancer (BC) is the most common cancer
type and is the leading cause of cancer-related death. There are two main histological …

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating
adaptive and maladaptive responses toward exogenous and endogenous signals …

Simple Summary The aryl hydrocarbon receptor (AhR) is expressed in breast cancer cells
and tumors and in some studies, the AhR is a negative prognostic factor for patient survival …

Simple Summary Cancer is driven by the excessive activity of growth-promoting genes and
deficient activity of the genes that restrain cell growth. Genes that suppress cell growth …

Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to
chemicals including polycyclic aromatic hydrocarbons (PAHs) and polychlorinated dibenzo …

Polycyclic aromatic hydrocarbons (PAHs), dioxin-like compounds (DLCs) and structurally-
related environmental pollutants may contribute to the pathogenesis of various diseases and …

Breast cancer is the most commonly diagnosed cancer among women worldwide. Despite a
variety of drugs available for the treatment of patients with breast cancer, drug resistance …

The aryl hydrocarbon receptor (AhR) is a crucial cytosolic evolutionary conserved ligand-
activated transcription factor and a pleiotropic signal transducer. The biosensor activity of the …

Breast cancer is the most common malignancy in women. Metastatic breast cancer is
incurable and is a major cause of shortened patient survival. The different molecular types of …