Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for MiR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice

M Barbosa, M Santos, N de Sousa, S Duarte-Silva… - Biomedicines, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with short life
expectancy and no effective therapy. We previously identified upregulated miR-124 in NSC …

[HTML][HTML] Electroacupuncture alleviates motor dysfunction by regulating neuromuscular junction disruption and neuronal degeneration in SOD1G93A mice

J Liu, W Zhao, J Guo, K Kang, H Li, X Yang, J Li… - Brain Research …, 2024 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease characterized by the
progressive destruction of the neuromuscular junction (NMJ) and the degeneration of motor …

Differential Distribution of SOD1 Variants in Submitochondrial Compartments: A Potential Pathological Mechanism in Amyotrophic Lateral Sclerosis

M Huang - 2024 - search.proquest.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by
progressive motor neuron (MN) degeneration. Superoxide dismutase 1 (SOD1) was the first …