MicroRNAs (miRNAs) are short, noncoding RNAs that posttranscriptionally regulate gene
expression. In the past decade, studies on miRNAs in ovaries have revealed the key roles of …

Primary ovarian insufficiency (POI) is defined as a reduction in ovarian function before the
expected age of menopause. POI is known to increase the risk of cardiovascular disorders …

It is estimated that infertility affects 15–20% of couples and can arise from female or male
reproductive defects. Mouse models have ascribed roles to over 100 genes in the …

It is well known that during mammalian ovarian follicular development, the majority of
follicles undergo atresia at various stages of their development. However, the mechanisms …

Autophagy is an important cellular process that serves as a companion pathway to the
ubiquitin-proteasome system to degrade long-lived proteins and organelles to maintain cell …

In all studies on programmed cell death (PCD) and apoptosis as its most showy form, this
process was considered to be a paradigmatic antithesis to necrotic cell death. On one hand …

Follicular atresia is primarily induced by granulosa cell apoptosis, but description of the
apoptotic pathway in granulosa cells is incomplete. In this study, we explored the possibility …

Background The mycotoxin zearalenone (ZEA) and its derivatives, alpha and beta-
zearalenol (alpha and beta-ZOL), synthesized by genera Fusarium, often occur as …

In mammals, the corpus luteum (CL) is a transient organ that secretes progesterone (P4). In
the absence of pregnancy, the CL undergoes regression (luteolysis), which is a crucial …

The effect of FSH on goat follicular development, granulosa cell apoptosis and
steroidogenesis and its mediation by insulin-like growth factor (IGF)-I were studied through …