Cells in vivo reside within complex microenvironments composed of both biochemical and
biophysical cues. The dynamic feedback between cells and their microenvironments hinges …

Since the cell was discovered by humans, it has been an important research subject for
researchers. The mechanical response of cells to external stimuli and the biomechanical …

Mechanical forces in the cell's natural environment have a crucial impact on growth,
differentiation and behaviour. Few areas of biology can be understood without taking into …

Implants are widely used in medical applications and yet macrophage-mediated foreign
body reactions caused by implants severely impact their therapeutic effects. Although the …

Living cells and tissues experience various complex modes of forces that are important in
physiology and disease. However, how different force modes impact gene expression is …

The development of biomaterials capable of regulating cellular processes and guiding cell
fate decisions has broad implications in tissue engineering, regenerative medicine, and cell …

Load-induced fluid flow acts as an important biophysical signal for bone cell
mechanotransduction in vivo, where the mechanical environment is thought to be monitored …

Angiogenesis, the formation of new bloods vessels from the existing vasculature, is a
process that is essential during development and regeneration of tissues, and that plays a …

Biological cells are exposed to a variety of mechanical loads throughout their life cycles that
eventually play an important role in a wide range of cellular processes. The understanding …

Investigating the effects of mechanical stimuli on stem cells under in vitro and in vivo
conditions is a very important issue to reach better control on cellular responses like growth …