Epstein–Barr virus and cancer

PJ Farrell - Annual Review of Pathology: Mechanisms of …, 2019 - annualreviews.org
Epstein–Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide,
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the …

Epstein–Barr virus: more than 50 years old and still providing surprises

LS Young, LF Yap, PG Murray - Nature reviews cancer, 2016 - nature.com
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

[HTML][HTML] Molecular basis of epstein–barr virus latency establishment and lytic reactivation

T Murata, A Sugimoto, T Inagaki, Y Yanagi… - Viruses, 2021 - mdpi.com
Epstein–Barr virus (EBV) is a causative agent of infectious mononucleosis and several types
of cancer. Like other herpesviruses, it establishes an asymptomatic, life-long latent infection …

Global trends in incidence and mortality of nasopharyngeal carcinoma

LL Tang, WQ Chen, WQ Xue, YQ He, RS Zheng… - Cancer letters, 2016 - Elsevier
Nasopharyngeal carcinoma (NPC) is a rare malignancy with an extraordinarily skewed
geographic distribution worldwide. Although decreasing trends in incidence and mortality of …

[HTML][HTML] Clinical and biological insights from viral genome sequencing

CJ Houldcroft, MA Beale, J Breuer - Nature Reviews Microbiology, 2017 - nature.com
Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not
only for basic research but also for clinical science and practice. In virology, WGS is …

[HTML][HTML] NK-/T-cell lymphomas

H Wang, B Fu, RP Gale, Y Liang - Leukemia, 2021 - nature.com
Natural killer/T-cell lymphoma (NKTL) is a sub-type of Epstein–Barr virus (EBV)-related non-
Hodgkin lymphomas common in Asia and Latin America but rare elsewhere. Its …

Current perspectives on nasopharyngeal carcinoma

HM Lee, KS Okuda, FE González, V Patel - … advances in cell models for the …, 2019 - Springer
Abstract Of the~ 129,079 new cases of nasopharyngeal carcinoma (NPC) and 72,987
associated deaths estimated for 2018, the majority will be geographically localized to South …

[HTML][HTML] The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

Defective Epstein–Barr virus in chronic active infection and haematological malignancy

Y Okuno, T Murata, Y Sato, H Muramatsu, Y Ito… - Nature …, 2019 - nature.com
Epstein–Barr virus (EBV) infection is highly prevalent in humans and is implicated in various
diseases, including cancer,. Chronic active EBV infection (CAEBV) is an intractable disease …

Epstein‐Barr virus strain variation and cancer

T Kanda, M Yajima, K Ikuta - Cancer science, 2019 - Wiley Online Library
Epstein‐Barr virus (EBV) is a human tumor virus and is etiologically linked to various
malignancies. Certain EBV‐associated diseases, such as Burkitt lymphomas and …