Multisystem physiological perspective of human frailty and its modulation by physical activity

JA Taylor, PL Greenhaff, DB Bartlett… - Physiological …, 2023 - journals.physiology.org
“Frailty” is a term used to refer to a state characterized by enhanced vulnerability to, and
impaired recovery from, stressors compared with a nonfrail state, which is increasingly …

[HTML][HTML] Inflammatory biomarkers of frailty: a review

L Zhang, X Zeng, F He, X Huang - Experimental gerontology, 2023 - Elsevier
Frailty is a common geriatric syndrome characterized by increased vulnerability and is
associated with adverse clinical events such as falls, hospitalization, and death. Early …

Frailty is related to serum inflammageing markers: results from the VITAL study

Y van Sleen, SA Shetty, M van der Heiden… - Immunity & …, 2023 - Springer
Frailty describes an age-associated state in individuals with an increased vulnerability and
less resilience against adverse outcomes. To score frailty, studies have employed the …

Inflammatory markers and physical frailty: towards clinical application

Y Pan, L Ma - Immunity & Ageing, 2024 - Springer
Global population aging poses a tremendous burden on the health care system worldwide.
Frailty is associated with decreased physical reserve and is considered an important …

Vitamin K contribution to DNA damage—advantage or disadvantage? A Human Health Response

J Kaźmierczak-Barańska, BT Karwowski - Nutrients, 2022 - mdpi.com
Vitamin K is the common name for a group of compounds recognized as essential for blood
clotting. The group comprises phylloquinone (K1)—a 2-methyl-3-phytyl-1, 4 …

The impact of age and number of mutations on the size of clonal hematopoiesis

K Wang, W Zhang, L Yi, M Zhao, PY Li… - Proceedings of the …, 2024 - National Acad Sciences
Clonal hematopoiesis (CH) represents the clonal expansion of hematopoietic stem cells and
their progeny driven by somatic mutations. Accurate risk assessment of CH is critical for …

Physical interventions restore physical frailty and the expression of CXCL-10 and IL-1β inflammatory biomarkers in old individuals and Mice

D Marcos-Pérez, S Cruces-Salguero… - Biomolecules, 2024 - mdpi.com
Background: Frailty is a geriatric syndrome associated with negative health outcomes that
represents a dynamic condition with a potential of reversibility after physical exercise …

[PDF][PDF] Vitamin K contribution to DNA damage-advantage or disadvantage? a human health response

J Kazmierczak-Baranska, BT Karwowski - Nutrients, 2022 - pdfs.semanticscholar.org
Vitamin K is the common name for a group of compounds recognized as essential for blood
clotting. The group comprises phylloquinone (K1)—a 2-methyl-3-phytyl-1, 4 …

Are skeletal muscle changes during prolonged space flights similar to those experienced by frail and sarcopenic older adults?

A Cannavo, A Carandina, G Corbi, E Tobaldini… - Life, 2022 - mdpi.com
Microgravity exposure causes several physiological and psychosocial alterations that
challenge astronauts' health during space flight. Notably, many of these changes are mostly …

Potential determinants of antibody responses after vaccination against SARS-CoV-2 in older persons: the Doetinchem Cohort Study

Y Kuijpers, HSJ Picavet, L de Rond… - Immunity & …, 2023 - Springer
Background Immune responses to vaccination vary widely between individuals. The aim of
this study was to identify health-related variables potentially underlying the antibody …