Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

For glioblastoma, the tumor microenvironment (TME) is pivotal to support tumor progression
and therapeutic resistance. TME consists of several types of stromal, endothelial and …

Objectives To determine patterns of ambulatory antibiotic prescribing in US adults, including
the use of broad-spectrum versus narrow-spectrum agents, to provide a description of the …

OBJECTIVES: Most ovarian cancer patients are diagnosed at an advanced stage (67%) and
prospects for significant improvement in survival reside in early diagnosis. While expression …

Chemotherapy, one of the principal approaches for cancer patients, plays a crucial role in
controlling tumor progression. Clinically, tumors reveal a satisfactory response following the …

Lung cancer is the leading cause of cancer-related deaths in the world, and non-small-cell
lung cancer (NSCLC) accounts for 80% of cases. MicroRNA-21 (miR-21) expression is …

MicroRNAs (miRNAs) are endogenous, small noncoding RNAs that play important roles in
various cellular functions and tumor development. Recent studies have indicated that miR …

• miR‐21 expression in cancer and other diseases• Mechanisms of miR‐21 elevation in
cancer: multi‐level regulatory control• Transcriptional control• Post‐trancriptional regulation• …

MicroRNAs (miRNAs or miRs) are small noncoding RNAs capable of regulating gene
expression at the translational level. Current evidence suggests that a significant portion of …

Small non-coding miRNAs (microRNAs) are emerging as key factors involved in cancer at
all stages ranging from initiation to metastasis. MIRN21 is an miRNA gene that codes for the …