Adult ADHD and comorbid disorders: clinical implications of a dimensional approach

MA Katzman, TS Bilkey, PR Chokka, A Fallu… - BMC psychiatry, 2017 - Springer
Attention-deficit/hyperactivity disorder (ADHD) in the adult population is frequently
associated with comorbid psychiatric diseases that complicate its recognition, diagnosis and …

Immune responses regulated by cannabidiol

JM Nichols, BLF Kaplan - Cannabis and cannabinoid research, 2020 - liebertpub.com
Introduction: Cannabidiol (CBD) as Epidiolex®(GW Pharmaceuticals) was recently
approved by the US Food and Drug Administration (FDA) to treat rare forms of epilepsy in …

Cannabidiol, neuroprotection and neuropsychiatric disorders

AC Campos, MV Fogaça, AB Sonego… - Pharmacological …, 2016 - Elsevier
Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis
sativa. It has possible therapeutic effects over a broad range of neuropsychiatric disorders …

New Methods for the Comprehensive Analysis of Bioactive Compounds in Cannabis sativa L. (hemp)

F Pellati, V Brighenti, J Sperlea, L Marchetti, D Bertelli… - Molecules, 2018 - mdpi.com
Cannabis sativa L. is a dioecious plant belonging to the Cannabaceae family. The main
phytochemicals that are found in this plant are represented by cannabinoids, flavones, and …

Cannabis and its secondary metabolites: their use as therapeutic drugs, toxicological aspects, and analytical determination

J Gonçalves, T Rosado, S Soares, AY Simão… - Medicines, 2019 - mdpi.com
Although the medicinal properties of Cannabis species have been known for centuries, the
interest on its main active secondary metabolites as therapeutic alternatives for several …

Efficacy and safety of cannabidiol plus standard care vs standard care alone for the treatment of emotional exhaustion and burnout among frontline health care …

JAS Crippa, AW Zuardi, FS Guimarães… - JAMA network …, 2021 - jamanetwork.com
Importance Frontline health care professionals who work with patients with COVID-19 have
an increased incidence of burnout symptoms. Cannabidiol (CBD) has anxiolytic and …

Cannabidiol as a promising strategy to treat and prevent movement disorders?

FF Peres, AC Lima, JEC Hallak, JA Crippa… - Frontiers in …, 2018 - frontiersin.org
Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating
conditions linked to oxidative stress and neurodegeneration. When available, the …

Pathophysiology and neurologic sequelae of cerebral malaria

N Schiess, A Villabona-Rueda, KE Cottier, K Huether… - Malaria journal, 2020 - Springer
Cerebral malaria (CM), results from Plasmodium falciparum infection, and has a high
mortality rate. CM survivors can retain life-long post CM sequelae, including seizures and …

Plastic and neuroprotective mechanisms involved in the therapeutic effects of cannabidiol in psychiatric disorders

AC Campos, MV Fogaça, FF Scarante… - Frontiers in …, 2017 - frontiersin.org
Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric
disorders, including anxiety, psychosis, and depression. The mechanisms responsible for …

Targeting cannabinoid signaling in the immune system:“High”-ly exciting questions, possibilities, and challenges

A Oláh, Z Szekanecz, T Bíró - Frontiers in Immunology, 2017 - frontiersin.org
It is well known that certain active ingredients of the plants of Cannabis genus, ie, the
“phytocannabinoids”[pCBs; eg,(−)-trans-Δ9-tetrahydrocannabinol (THC),(−)-cannabidiol …