Therapeutic drug monitoring of oral targeted antineoplastic drugs
A Mueller-Schoell, SL Groenland… - European journal of …, 2021 - Springer
Purpose This review provides an overview of the current challenges in oral targeted
antineoplastic drug (OAD) dosing and outlines the unexploited value of therapeutic drug …
antineoplastic drug (OAD) dosing and outlines the unexploited value of therapeutic drug …
The dosing and monitoring of vancomycin: what is the best way forward?
We have evaluated the literature to review optimal dosing and monitoring of intravenous
vancomycin in adults, in response to evolving understanding of targets associated with …
vancomycin in adults, in response to evolving understanding of targets associated with …
Application of machine learning classification to improve the performance of vancomycin therapeutic drug monitoring
Bayesian therapeutic drug monitoring (TDM) software uses a reported pharmacokinetic (PK)
model as prior information. Since its estimation is based on the Bayesian method, the …
model as prior information. Since its estimation is based on the Bayesian method, the …
Personalized dosing of infliximab in patients with inflammatory bowel disease using a Bayesian approach: a next step in therapeutic drug monitoring
Although biological agents have revolutionized the management of inflammatory bowel
diseases (IBDs), a significant proportion of patients show primary non‐response or develop …
diseases (IBDs), a significant proportion of patients show primary non‐response or develop …
Semi-automated therapeutic drug monitoring as a pillar toward personalized medicine for tuberculosis management
Standard tuberculosis (TB) management has failed to control the growing number of drug-
resistant TB cases worldwide. Therefore, innovative approaches are required to eradicate …
resistant TB cases worldwide. Therefore, innovative approaches are required to eradicate …
Right dose, right now: development of autokinetics for real time model informed precision antibiotic dosing decision support at the bedside of critically ill patients
LF Roggeveen, T Guo, RH Driessen… - Frontiers in …, 2020 - frontiersin.org
Introduction Antibiotic dosing in critically ill patients is challenging because their
pharmacokinetics (PK) are altered and may change rapidly with disease progression …
pharmacokinetics (PK) are altered and may change rapidly with disease progression …
Predictive performance of Bayesian vancomycin monitoring in the critically ill
OBJECTIVES: It is recommended that therapeutic monitoring of vancomycin should be
guided by 24-hour area under the curve concentration. This can be done via Bayesian …
guided by 24-hour area under the curve concentration. This can be done via Bayesian …
PBPK modeling and simulation and therapeutic drug monitoring: Possible ways for antibiotic dose adjustment
Pharmacokinetics (PK) is a branch of pharmacology present and of vital importance for the
research and development (R&D) of new drugs, post-market monitoring, and continued …
research and development (R&D) of new drugs, post-market monitoring, and continued …
Bayesian forecasting for intravenous tobramycin dosing in adults with cystic fibrosis using one versus two serum concentrations in a dosing interval
PG Drennan, Y Thoma, L Barry, J Matthey… - Therapeutic Drug …, 2021 - journals.lww.com
Background: Intravenous tobramycin treatment requires therapeutic drug monitoring (TDM)
to ensure safety and efficacy when used for prolonged treatment, as in infective …
to ensure safety and efficacy when used for prolonged treatment, as in infective …
[HTML][HTML] Assessment of an institutional guideline for vancomycin dosing and identification of predictive factors associated with dose and drug trough levels
Objectives To evaluate the effectiveness of an antimicrobial guideline for vancomycin
prescribing deployed using electronic prescribing aid and web/phone-based app. To define …
prescribing deployed using electronic prescribing aid and web/phone-based app. To define …