Biological and physiological role of reactive oxygen species–the good, the bad and the ugly

L Zuo, T Zhou, BK Pannell, AC Ziegler… - Acta …, 2015 - Wiley Online Library
Reactive oxygen species (ROS) are chemically reactive molecules that are naturally
produced within biological systems. Research has focused extensively on revealing the …

Melatonin: a versatile protector against oxidative DNA damage

A Galano, DX Tan, RJ Reiter - Molecules, 2018 - mdpi.com
Oxidative damage to DNA has important implications for human health and has been
identified as a key factor in the onset and development of numerous diseases. Thus, it is …

Cardiovascular reactivity, stress, and physical activity

CJ Huang, HE Webb, MC Zourdos… - Frontiers in …, 2013 - frontiersin.org
Psychological stress has been proposed as a major contributor to the progression of
cardiovascular disease (CVD). Acute mental stress can activate the sympathetic-adrenal …

The role of hypoxia-induced factors in tumor progression

P Vaupel - The oncologist, 2004 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Describe hypoxia-induced mechanisms for cell survival. Discuss hypoxia-induced gene …

Oxidative stress in prostate cancer

L Khandrika, B Kumar, S Koul, P Maroni, HK Koul - Cancer letters, 2009 - Elsevier
As prostate cancer and aberrant changes in reactive oxygen species (ROS) become more
common with aging, ROS signaling may play an important role in the development and …

CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life

S Elchuri, TD Oberley, W Qi, RS Eisenstein… - Oncogene, 2005 - nature.com
Mice deficient in CuZn superoxide dismutase (CuZnSOD) showed no overt abnormalities
during development and early adulthood, but had a reduced lifespan and increased …

Genotoxicity and potential carcinogenicity of cyanobacterial toxins–a review

B Žegura, A Štraser, M Filipič - Mutation Research/Reviews in Mutation …, 2011 - Elsevier
The occurrence of cyanobacterial blooms has increased significantly in many regions of the
world in the last century due to water eutrophication. These blooms are hazardous to …

Prostate carcinogenesis and inflammation: emerging insights

GS Palapattu, S Sutcliffe, PJ Bastian, EA Platz… - …, 2005 - academic.oup.com
Prostate cancer remains a significant health concern for men throughout the world. Recently,
there has developed an expanding multidisciplinary body of literature suggesting a link …

Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease

M Hüttemann, I Lee, A Pecinova, P Pecina… - Journal of bioenergetics …, 2008 - Springer
Abstract Thirty years after Peter Mitchell was awarded the Nobel Prize for the chemiosmotic
hypothesis, which links the mitochondrial membrane potential generated by the proton …

Essential Oil of Myrtus communis L. as a Potential Antioxidant and Antimutagenic Agents

N Mimica-Dukić, D Bugarin, S Grbović, D Mitić-Ćulafić… - Molecules, 2010 - mdpi.com
The present study describes DPPH (2, 2-diphenyl-1-picrylhydrazyl) radical scavenging
activity and antimutagenic properties of the essential oil of myrtle (Myrtus communis L.) …