Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Bioengineering of microalgae: recent advances, perspectives, and regulatory challenges for industrial application

G Kumar, A Shekh, S Jakhu, Y Sharma… - … in Bioengineering and …, 2020 - frontiersin.org
Microalgae, due to their complex metabolic capacity, are being continuously explored for
nutraceuticals, pharmaceuticals, and other industrially important bioactives. However …

A deep learning model to predict RNA-Seq expression of tumours from whole slide images

B Schmauch, A Romagnoni, E Pronier… - Nature …, 2020 - nature.com
Deep learning methods for digital pathology analysis are an effective way to address
multiple clinical questions, from diagnosis to prediction of treatment outcomes. These …

Paving the way to single-molecule protein sequencing

L Restrepo-Pérez, C Joo, C Dekker - Nature nanotechnology, 2018 - nature.com
Proteins are major building blocks of life. The protein content of a cell and an organism
provides key information for the understanding of biological processes and disease. Despite …

Clustering of single-cell multi-omics data with a multimodal deep learning method

X Lin, T Tian, Z Wei, H Hakonarson - Nature communications, 2022 - nature.com
Single-cell multimodal sequencing technologies are developed to simultaneously profile
different modalities of data in the same cell. It provides a unique opportunity to jointly …

From big data analysis to personalized medicine for all: challenges and opportunities

A Alyass, M Turcotte, D Meyre - BMC medical genomics, 2015 - Springer
Recent advances in high-throughput technologies have led to the emergence of systems
biology as a holistic science to achieve more precise modeling of complex diseases. Many …

Seed priming: new comprehensive approaches for an old empirical technique

S Lutts, P Benincasa, L Wojtyla, S Kubala… - New challenges in …, 2016 - books.google.com
Seed priming is a pre-sowing treatment which leads to a physiological state that enables
seed to germinate more efficiently. The majority of seed treatments are based on seed …

Integrating proteomics and transcriptomics for systematic combinatorial chimeric antigen receptor therapy of AML

F Perna, SH Berman, RK Soni, J Mansilla-Soto… - Cancer cell, 2017 - cell.com
Chimeric antigen receptor (CAR) therapy targeting CD19 has yielded remarkable outcomes
in patients with acute lymphoblastic leukemia. To identify potential CAR targets in acute …

Fungal enzymes for bio-products from sustainable and waste biomass

VK Gupta, CP Kubicek, JG Berrin, DW Wilson… - Trends in biochemical …, 2016 - cell.com
Lignocellulose, the most abundant renewable carbon source on earth, is the logical
candidate to replace fossil carbon as the major biofuel raw material. Nevertheless, the …

Appetite-controlling endocrine systems in teleosts

I Rønnestad, AS Gomes, K Murashita… - Frontiers in …, 2017 - frontiersin.org
Mammalian studies have shaped our understanding of the endocrine control of appetite and
body weight in vertebrates and provided the basic vertebrate model that involves central …