The role of thiamine in cancer: possible genetic and cellular signaling mechanisms

KVQ LU'O'NG, LTH Nguyễn - Cancer genomics & proteomics, 2013 - cgp.iiarjournals.org
The relationship between supplemental vitamins and various types of cancer has been the
focus of recent investigation, and supplemental vitamins have been reported to modulate …

Matrix metalloproteinases and genetic mouse models in cancer research: a mini-review

E Wieczorek, E Jablonska, W Wasowicz, E Reszka - Tumor Biology, 2015 - Springer
Carcinogenesis is a multistep and also a multifactorial process that involves agents like
genetic and environmental factors. Matrix metalloproteinases (MMPs) are major proteolytic …

[HTML][HTML] Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits

JU Marquardt, D Seo, JB Andersen, MC Gillen… - Journal of …, 2014 - Elsevier
Background & Aims Human hepatocarcinogenesis is as a multi-step process starting from
dysplastic lesions to early carcinomas (eHCC) that ultimately progress to HCC (pHCC) …

G labridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase 9 through modulation of NF‐κ B and AP‐1 activity in human liver …

MJ Hsieh, CW Lin, SF Yang, MK Chen… - British Journal of …, 2014 - Wiley Online Library
Background and Purpose High mortality and morbidity rates for hepatocellular carcinoma in
T aiwan primarily result from uncontrolled tumour metastasis. G labridin, a prenylated …

MMP-14 overexpression correlates with poor prognosis in non-small cell lung cancer

Y Wang, K Wu, A Wu, Z Yang, J Li, Y Mo, M Xu, B Wu… - Tumor Biology, 2014 - Springer
Abstract Matrix metalloproteinase-14 (MMP-14) has been demonstrated to play an important
role in tumor progression. The aim of this study was to analyze the correlation between MMP …

Membrane type 1-matrix metalloproteinase induces epithelial-to-mesenchymal transition in esophageal squamous cell carcinoma: Observations from clinical and in …

L Pang, Q Li, S Li, J He, W Cao, J Lan, B Sun, H Zou… - Scientific reports, 2016 - nature.com
Membrane type 1-matrix metalloproteinase (MT1-MMP) is associated with enhanced
tumorigenicity in many cancers. A recent study has revealed that MT1-MMP induces …

Diosmetin inhibits the metastasis of hepatocellular carcinoma cells by downregulating the expression levels of MMP‑2 and MMP‑9

J Liu, X Wen, B Liu, Q Zhang… - Molecular …, 2016 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most malignant types of tumor worldwide with
a high rate of mortality. Diosmetin (DIOS) exhibits various activities, including anticancer …

β‐mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP‐2 and MMP‐9 expression and activating the ERK and JNK …

CF Huang, YH Teng, FJ Lu, WH Hsu… - Environmental …, 2017 - Wiley Online Library
Abstract β‐mangostin is a dietary xanthone that has been reported to have the anticancer
properties in some human cancer cell types. However, the antimetastatic effect and …

11-epi-Sinulariolide Acetate Reduces Cell Migration and Invasion of Human Hepatocellular Carcinoma by Reducing the Activation of ERK1/2, p38MAPK and FAK …

JJ Lin, JH Su, CC Tsai, YJ Chen, MH Liao, YJ Wu - Marine drugs, 2014 - mdpi.com
Cancer metastasis is one of the major causes of death in cancer. An active compound, 11-
epi-sinulariolide acetate (11-epi-SA), isolated from the cultured soft coral Sinularia flexibilis …

The antimetastatic effects of resveratrol on hepatocellular carcinoma through the downregulation of a metastasis-associated protease by SP-1 modulation

CB Yeh, MJ Hsieh, CW Lin, HL Chiou, PY Lin… - PloS one, 2013 - journals.plos.org
Background The mortality and morbidity rates from cancer metastasis have not declined in
Taiwan, especially because of hepatocellular carcinoma (HCC). Resveratrol has been …