Johnson1 proposed that obesity, insulin resistance (IR), and laminitis were components of a
clinical syndrome recognized in horses and ponies. The study of EMS is therefore in its …

Veterinarians have long recognized that obese horses and ponies are prone to laminitis, but
the concept of an equine metabolic syndrome (EMS) was first proposed by Johnson 1 in …

Insulin dysregulation is the hallmark of equine metabolic syndrome and has received
attention because of its direct association with laminitis. In the absence of an adequate …

The aim of this study was to investigate the relationship between laminitis development in
ponies and insulin/glucose concentrations in response to the oral glucose test (OGT) and a …

Background The importance of including exercise with dietary modification for the
management of obese equids is not clearly understood. Objectives To evaluate the effect of …

Excessive BW has become a major health issue in the equine (Equus caballus) industry.
The objectives were to determine if the addition of neck circumference and height improved …

Although much has been written about laminitis in the context of its association with
inflammatory processes, such as dietary carbohydrate overload and endotoxemia, 1–5 …

Metformin may be an effective therapeutic option for insulin-resistant (IR) horses/ponies
because, in humans, it reportedly enhances insulin sensitivity (SI) of peripheral tissues …

Obesity has become a serious health problem with frequent occurrence both in human and
animal populations. It is estimated that it may affect over 85% of the human population and …

Lamellar pathology in experimentally-induced equine laminitis associated with euglycaemic
hyperinsulinaemia is substantial by the acute, clinical phase (∼ 48h post-induction) …