The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

Cycloaddition reactions in organic chemistry are not only among the synthetically most
useful reactions, they are also among the theoretically and mechanistically best understood …

Few areas of synthetic chemistry have witnessed growth as explosive as that brought about
by the ap-plication of lanthanide reagents to organic synthesis. Long ignored in the arena of …

The importance of tandem reactions is evident--besides their pragmatic value, they have an
aesthetic appeal. The author presents a survey of these reactions that will rivet the attention …

Terpenoids are among Nature's more versatile and exciting creations. In a remarkable
display of synthetic ingenuity and creativity, Nature has endowed terpenes with a …

The Pauson±Khand (P±K) reaction, formally a [21211] cycloaddition involving an alkene, an
alkyne and carbon monoxide moieties to form a cyclopentenone, was first discovered in the …

The Pauson–Khand reaction (PKR) is a cocyclization of alkynes with alkenes and carbon
monoxide by dicobalt octacarbonyl leading to cyclopentenones and has become one of the …

Ein neues Jahrtausend hat begonnen–Grund genug, sich die Frage zu stellen, welchen
Stand die Totalsynthese von Naturstoffen erreicht hat. Dieser Aufsatz möchte eine Antwort …

We report an asymmetric, catalytic transannular aldolization that provides polycyclic
products useful for natural product synthesis. We found that a proline-derivative catalyzes …

The transition-metal promoted cyclocondensation of an alkyne, alkene, and carbon
monoxide (the Pauson-Khand reaction when cobalt complexes are employed) has emerged …