Sulfonamides constitute an important class of drugs, with many types of pharmacological
agents possessing antibacterial, anti-carbonic anhydrase, anti-obesity, diuretic …

Nowadays, the scientific community has focused on dealing with different kinds of diseases
by exploring the chemistry of various heterocycles as novel drugs. In this connection …

A series of coumarin‐linked thiazoles (6a–p) was synthesized and the synthesized
compounds were evaluated against human carbonic anhydrases (hCAs) IX and XII, which …

Carbonic anhydrase CA-II enzyme is essential for maintaining homeostasis in several
processes, including respiration, lipogenesis, gluconeogenesis, calcification, bone …

Abstract Phenylthiazol-2 (3h)-ylidene-isoquinoline-5-amine derivatives (5a-r) were easily
prepared from 5-aminoisoquinoline, thioisocyanate, and phenacyl bromide derivatives in the …

Carbonic anhydrase (CA) is a zinc metalloenzyme that facilitates the rapid conversion of
water and carbon dioxide into proton and bicarbonate ion. CA isozymes have been broadly …

Objective: This study involved the synthesis of new Schiff bases and 1, 3-oxazepine
derivatives from the baclofen drug and study the anticancer activities. Methods: Baclofen …

New substituted heterocyclic compounds 2a–2c were synthesized from N-(6-hydrazinyl-6-
oxohexanoyl) phthalimide, and their structure was confirmed by FT-IR, 1H NMR, and 13C …

The reaction medium plays a key role in organic synthesis and pharmaceutical research.
There are many opinions on choosing the best condition, including cost and environmental …

Flavonoid ailesinin üyeleri çok çeşitli biyolojik aktivitelere sahiptir ve doğal bileşiklerin bu
grubu meyveler, bitkiler, tohumlar, yapraklar ve birçok çiçekte bulunmaktadır. Doğal veya …