Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …

Ruthenium is seldom mentioned in microbiology texts, due to the fact that this metal has no
known, essential roles in biological systems, nor is it generally considered toxic. Since the …

Ruthenium (II) complexes are currently considered a viable alternative to the widely used
platinum complexes as efficient anticancer agents. We herein present the synthesis and …

A group of seventeen communicable and poverty-related diseases are considered
neglected by the World Health Organization due to the restricted development of diagnostic …

Thiazole, thiosemicarbazone and semicarbazone moieties are privileged scaffolds (acting
as primary pharmacophores) in many compounds that are useful to treat several diseases …

Four new Cu (I) complexes of the general formula [Cu (PP)(LL)][BF4], in which PP is a
phosphane ligand (triphenylphosphane or 1, 2‐bis (diphenylphosphano) ethane (dppe)) …

Toxoplasma gondii is an apicomplexan parasite that infects and proliferates within many
different types of host cells and infects virtually all warm-blooded animals and humans …

American Trypanosomiasis is a chronic infection discovered and described in 1909 by the
Brazilian scientist Carlos Chagas. It is caused by the protozoan parasite Trypanosoma cruzi …