Conspectus Chain-walking offers extensive opportunities for innovating synthetic methods
that involve constructing chemical bonds at unconventional sites. This approach provides …

Migration of metals along a carbon chain is triggered by two of the most common
organometallic elementary steps–β-hydride (β-H) elimination and alkene hydrometallation …

While chain‐walking stimulates wide interest in both polymerization and organic synthesis,
site‐and stereoselective control of chain‐walking on rings is still a challenging task in the …

Metal‐catalyzed chain‐walking reactions have recently emerged as a powerful strategy to
functionalize remote positions in organic molecules. However, a chain‐walking protocol for …

Chain walking has been an efficient route to realize the functionalization of inert C (sp3)− H
bonds, but this strategy is limited to mono‐olefin migration and functionalization. Herein, we …

Past several decades have witnessed the great evolution of inert C–H bond functionalization
reactions as an emerging technique for synthesizing drug molecules, agrochemicals, and …

The successful realization of gold‐catalyzed chain‐walking reactions, facilitated by ligand‐
enabled Au (I)/Au (III) redox catalysis, has been reported for the first time. This breakthrough …

The enantioselective catalytic cascade involving Tsuji–Trost allylation has provided a viable
strategy for the construction of multiple asymmetric C–C and C–X centres and numerous …

Transition metal-catalyzed asymmetric allylic substitution with a suitably pre-stored leaving
group in the substrate is widely used in organic synthesis. In contrast, the enantioselective …

Despite the long-standing exploration of the catalytic asymmetric Tsuji–Trost allylation
reaction since the mid-20th century, most reported instances have adhered to a two …