[HTML][HTML] Differential rearrangement of excitatory inputs to the medial prefrontal cortex in chronic pain models
T Jefferson, CJ Kelly, M Martina - Frontiers in neural circuits, 2021 - frontiersin.org
Chronic pain patients suffer a disrupted quality of life not only from the experience of pain
itself, but also from comorbid symptoms such as depression, anxiety, cognitive impairment …
itself, but also from comorbid symptoms such as depression, anxiety, cognitive impairment …
Sex and gender differences in pain
NR Osborne, KD Davis - International Review of Neurobiology, 2022 - Elsevier
Chronic pain affects 20% of adults and is one of the leading causes of disability worldwide.
Women and girls are disproportionally affected by chronic pain. About half of chronic pain …
Women and girls are disproportionally affected by chronic pain. About half of chronic pain …
[HTML][HTML] Exercise training augments brain function and reduces pain perception in adults with chronic pain: A systematic review of intervention studies
Introduction Chronic pain (CP) is a leading cause of disability worldwide. Pain may be
measured using subjective questionnaires, but understanding the underlying physiology …
measured using subjective questionnaires, but understanding the underlying physiology …
[HTML][HTML] Activation of the dorsal, but not the ventral, hippocampus relieves neuropathic pain in rodents
X Wei, MV Centeno, W Ren, AM Borruto, D Procissi… - Pain, 2021 - journals.lww.com
Accumulating evidence suggests hippocampal impairment under the chronic pain
phenotype. However, it is unknown whether neuropathic behaviors are related to …
phenotype. However, it is unknown whether neuropathic behaviors are related to …
Altered habenular connectivity in chronic low back pain: An fMRI and machine learning study
CP Mao, Y Wu, HJ Yang, J Qin, QC Song… - Human Brain …, 2023 - Wiley Online Library
The habenula has been implicated in the pathogenesis of pain and analgesia, while
evidence concerning its function in chronic low back pain (cLBP) is sparse. This study aims …
evidence concerning its function in chronic low back pain (cLBP) is sparse. This study aims …
[HTML][HTML] Altered resting-state functional connectivity within corticostriatal and subcortical-striatal circuits in chronic pain
Brain corticostriatal circuits are important for understanding chronic pain and highly relevant
to motivation and cognitive processes. It has been demonstrated that in patients with chronic …
to motivation and cognitive processes. It has been demonstrated that in patients with chronic …
[HTML][HTML] Pain relief reverses hippocampal abnormalities in trigeminal neuralgia
Chronic pain patients frequently report memory and concentration difficulties. Objective
testing in this population points to poor performance on memory and cognitive tests, and …
testing in this population points to poor performance on memory and cognitive tests, and …
[HTML][HTML] Burning fog: cognitive impairment in burning mouth syndrome
Background: Due to its common association with chronic pain experience, cognitive
impairment (CI) has never been evaluated in patients with burning mouth syndrome (BMS) …
impairment (CI) has never been evaluated in patients with burning mouth syndrome (BMS) …
[HTML][HTML] Hippocampal volume, FKBP5 genetic risk alleles, and childhood trauma interact to increase vulnerability to chronic multisite musculoskeletal pain
Chronic multisite musculoskeletal pain (CMP) is common and highly morbid. However,
vulnerability factors for CMP are poorly understood. Previous studies have independently …
vulnerability factors for CMP are poorly understood. Previous studies have independently …
Abnormal subgenual anterior cingulate circuitry is unique to women but not men with chronic pain
The subgenual anterior cingulate cortex (sgACC) plays an important role in pain modulation.
We previously demonstrated sex differences in sgACC functional connectivity (FC) in …
We previously demonstrated sex differences in sgACC functional connectivity (FC) in …