Plant-derived human vaccines: Recent developments

J Stander, S Mbewana, AE Meyers - BioDrugs, 2022 - Springer
The idea of producing vaccines in plants originated in the late 1980s. Initially, it was
contemplated that this notion could facilitate the concept of edible vaccines, making them …

Plant-made vaccines against viral diseases in humans and farm animals

H Su, A Van Eerde, E Rimstad, R Bock… - Frontiers in plant …, 2023 - frontiersin.org
Plants provide not only food and feed, but also herbal medicines and various raw materials
for industry. Moreover, plants can be green factories producing high value bioproducts such …

Construction of SARS-CoV-2 virus-like particles in plant

KB Moon, JH Jeon, H Choi, JS Park, SJ Park, HJ Lee… - Scientific reports, 2022 - nature.com
Abstract The pandemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) has caused a public health emergency, and research on the development of various …

The plant viruses and molecular farming: how beneficial they might be for human and animal health?

G Zahmanova, AA Aljabali, K Takova, V Toneva… - International Journal of …, 2023 - mdpi.com
Plant viruses have traditionally been studied as pathogens in the context of understanding
the molecular and cellular mechanisms of a particular disease affecting crops. In recent …

The re-emergence of hepatitis E virus in Europe and vaccine development

G Zahmanova, K Takova, V Tonova, T Koynarski… - Viruses, 2023 - mdpi.com
Hepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. Transmission of
HEV mainly occurs via the fecal-oral route (ingesting contaminated water or food) or by …

Combating human viral diseases: will plant-based vaccines be the answer?

S Venkataraman, K Hefferon, A Makhzoum… - Vaccines, 2021 - mdpi.com
Molecular pharming or the technology of application of plants and plant cell culture to
manufacture high-value recombinant proteins has progressed a long way over the last three …

Plant-derived VLP: a worthy platform to produce vaccine against SARS-CoV-2

F Hemmati, M Hemmati-Dinarvand, M Karimzade… - Biotechnology …, 2022 - Springer
After its emergence in late 2019 SARS-CoV-2 was declared a pandemic by the World Health
Organization on 11 March 2020 and has claimed more than 2.8 million lives. There has …

Development of virus‐like particles‐based vaccines against coronaviruses

CY Yong, WPP Liew, HK Ong… - Biotechnology Progress, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus (SARS‐CoV), Middle East respiratory
syndrome coronavirus (MERS‐CoV), and the current severe acute respiratory syndrome …

Producing vaccines against enveloped viruses in plants: Making the impossible, difficult

H Peyret, JFC Steele, JW Jung, EC Thuenemann… - Vaccines, 2021 - mdpi.com
The past 30 years have seen the growth of plant molecular farming as an approach to the
production of recombinant proteins for pharmaceutical and biotechnological uses. Much of …

A comprehensive overview on the production of vaccines in plant-based expression systems and the scope of plant biotechnology to combat against SARS-CoV-2 …

M Kumar, N Kumari, N Thakur, SK Bhatia, GD Saratale… - Plants, 2021 - mdpi.com
Many pathogenic viral pandemics have caused threats to global health; the COVID-19
pandemic is the latest. Its transmission is growing exponentially all around the globe, putting …