On the road to the brain-on-a-chip: a review on strategies, methods, and applications
The brain is the most complex organ of our body. Such a complexity spans from the single-
cell morphology up to the intricate connections that hundreds of thousands of neurons …
cell morphology up to the intricate connections that hundreds of thousands of neurons …
Brain slice on a chip: opportunities and challenges of applying microfluidic technology to intact tissues
Y Huang, JC Williams, SM Johnson - Lab on a Chip, 2012 - pubs.rsc.org
Isolated brain tissue, especially brain slices, are valuable experimental tools for studying
neuronal function at the network, cellular, synaptic, and single channel levels …
neuronal function at the network, cellular, synaptic, and single channel levels …
Active pixel sensor array for high spatio-temporal resolution electrophysiological recordings from single cell to large scale neuronal networks
L Berdondini, K Imfeld, A Maccione, M Tedesco… - Lab on a Chip, 2009 - pubs.rsc.org
This paper presents a chip-based electrophysiological platform enabling the study of micro-
and macro-circuitry in in-vitro neuronal preparations. The approach is based on a 64× 64 …
and macro-circuitry in in-vitro neuronal preparations. The approach is based on a 64× 64 …
A three-dimensional multi-electrode array for multi-site stimulation and recording in acute brain slices
MO Heuschkel, M Fejtl, M Raggenbass… - Journal of neuroscience …, 2002 - Elsevier
Several multi-electrode array devices integrating planar metal electrodes were designed in
the past 30 years for extracellular stimulation and recording from cultured neuronal cells and …
the past 30 years for extracellular stimulation and recording from cultured neuronal cells and …
A novel organotypic long-term culture of the rat hippocampus on substrate-integrated multielectrode arrays
U Egert, B Schlosshauer, S Fennrich, W Nisch… - Brain Research …, 1998 - Elsevier
Spatiotemporally coordinated activity of neural networks is crucial for brain functioning. To
understand the basis of physiological information processing and pathological states …
understand the basis of physiological information processing and pathological states …
Markers for neuronal degeneration in organotypic slice cultures
J Noraberg, BW Kristensen, J Zimmer - Brain research protocols, 1999 - Elsevier
This protocol describes ways of monitoring spontaneous or induced neuronal degeneration
in organotypic brain slice cultures. Hippocampal cultures (4-week-old) are grown in normal …
in organotypic brain slice cultures. Hippocampal cultures (4-week-old) are grown in normal …
Development of in vitro 2D and 3D microelectrode arrays and their role in advancing biomedical research
The development of microelectrode arrays (MEAs) along with complementary advances in
electronics, mechanics and software to connect with these arrays has led to the in vitro …
electronics, mechanics and software to connect with these arrays has led to the in vitro …
Nanostructured gold microelectrodes for extracellular recording from electrogenic cells
We present a new biocompatible nanostructured microelectrode array for extracellular
signal recording from electrogenic cells. Microfabrication techniques were combined with a …
signal recording from electrogenic cells. Microfabrication techniques were combined with a …
[图书][B] Advances in network electrophysiology
M Taketani, M Baudry - 2010 - Springer
Advances in network electrophysiology Page 2 Advances in Network Electrophysiology i Page 3
Makoto Taketani Michel Baudry Editors Advances in Network Electrophysiology Using …
Makoto Taketani Michel Baudry Editors Advances in Network Electrophysiology Using …
Electrophysiology read-out tools for brain-on-chip biotechnology
Brain-on-Chip (BoC) biotechnology is emerging as a promising tool for biomedical and
pharmaceutical research applied to the neurosciences. At the convergence between lab-on …
pharmaceutical research applied to the neurosciences. At the convergence between lab-on …