[HTML][HTML] Differential expression of haptoglobin in individuals at clinical high risk of psychosis and its association with global functioning and clinical symptoms

C Healy, J Byrne, SR Suasi, M Föcking… - Brain, Behavior, and …, 2024 - Elsevier
Background Immune dysregulation has been observed in patients with schizophrenia or first-
episode psychosis, but few have examined dysregulation in those at clinical high-risk (CHR) …

[HTML][HTML] Prospects and pitfalls of plasma complement C4 in schizophrenia: Building a better biomarker

EG Severance, E Prandovszky, S Yang… - Developmental …, 2023 - karger.com
Complex brain disorders like schizophrenia may have multifactorial origins related to mis-
timed heritable and environmental factors interacting during neurodevelopment. Infections …

Proteomic biomarkers for the prediction of transition to psychosis in individuals at clinical high risk: a multi-cohort model development study

JF Byrne, C Healy, M Föcking, SR Susai… - Schizophrenia …, 2024 - academic.oup.com
Psychosis risk prediction is one of the leading challenges in psychiatry. Previous
investigations have suggested that plasma proteomic data may be useful in accurately …

[HTML][HTML] Plasma complement and coagulation proteins as prognostic factors of negative symptoms: An analysis of the NAPLS 2 and 3 studies

JF Byrne, C Healy, M Föcking, M Heurich… - Brain, Behavior, and …, 2024 - Elsevier
Introduction Negative symptoms impact the quality of life of individuals with psychosis and
current treatment options for negative symptoms have limited effectiveness. Previous studies …

Artificial intelligence applications in mental health: the state of the art

A Zucchetti, G Nibbio, L Altieri… - Italian Journal of …, 2024 - italianjournalofpsychiatry.it
Objectives. This review aims to examine the current use of artificial intelligence (AI) in mental
health. The first step involves categorising AI algorithms into three subtypes: natural …