Pancreatitis is inflammation of pancreas and caused by a number of factors including
pancreatic duct obstruction, alcoholism, and mutation in the cationic trypsinogen gene …

Animal models of acute and chronic pancreatitis have been created to examine mechanisms
of pathogenesis, test therapeutic interventions, and study the influence of inflammation on …

Inflammation and autophagy are cellular defense mechanisms. When these processes are
deregulated (deficient or overactivated) they produce pathologic effects, such as oxidative …

Immune cells are important in the pathogenesis of acute pancreatitis and determine disease
severity. Results from cytokine-based clinical trials for acute pancreatitis have been …

The immune system plays a complex role in the development and progression of pancreatic
cancer. Inflammation can promote the formation of premalignant lesions and accelerate …

Background Pancreatitis in cats, although commonly diagnosed, still presents many
diagnostic and management challenges. Objective To summarize the current literature as it …

Objective Long-standing chronic pancreatitis is an established risk factor for pancreatic
ductal adenocarcinoma (PDAC). Interleukin-1β (IL-1β) has been associated in PDAC with …

Acute pancreatitis is an inflammatory disease characterized by interstitial edema,
inflammatory cell infiltration, and acinar cell necrosis, depending on its severity. Regardless …

Background & Aims Little is known about the pathogenic mechanisms of chronic
pancreatitis. We investigated the roles of complement component 5 (C5) in pancreatic …

Background: Previous epidemiologic studies suggest associations between preterm birth
and ambient air pollution. Objective: We investigated associations between 11 ambient air …