Until today the role of oxygen in the development of the fetus remains controversially
discussed. It is still believed that lack of oxygen in utero might be responsible for some of the …

Implantation failure and inadequate placental development are important contributors to
infertility, recurrent miscarriage, and other pregnancy-related problems in women. Better …

Embryo implantation in higher primates is mediated by trophoblast: in the earliest phases by
syncytiotrophoblast, then by both cytotrophoblast and syncytiotrophoblast. In the course of …

Migration of extravillous trophoblasts (EVT) into decidua and myometrium is a critical
process in the conversion of maternal spiral arterioles and establishing placenta perfusion …

Placental explant cultures in vitro are useful for studying tissue functions including cellular
uptake, production and release of secretory components, cell interactions, proliferation …

Interleukin-8 (IL8/CXCL8) is present in decidua and trophoblast, which also expresses the
IL8 receptors, CXCR1 and CXCR2. IL8 was shown to stimulate trophoblast migration. Matrix …

Le placenta humain est une structure invasive dans laquelle les cellules du trophoblaste
extravilleux (TEV), très prolifératives, migratrices et invasives, migrent et envahissent l'utérus …

Impaired trophoblast invasiveness and spiral arterial remodelling, which results in poor
placental perfusion during early pregnancy, is believed to cause fetal injury and growth …

In humans, the placenta provides the only fetomaternal connection and is essential for
establishing a pregnancy as well as fetal well-being. Additionally, it allows maternal …

We have earlier shown that migration and invasiveness of first trimester human extravillous
trophoblast cells are stimulated by IGF-II, independently of IGF type 1 receptor and that …