A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …

The human preterm brain is particularly susceptible to cerebral white matter injury (WMI) that
disrupts the normal progression of developmental myelination. Advances in the care of …

Hypoxic-ischemic and traumatic brain injuries are leading causes of long-term mortality and
disability in infants and children. Although several preclinical models using rodents of …

Oligodendrogenesis occurs during early postnatal development, coincident with
neurogenesis and synaptogenesis, raising the possibility that microglia-dependent pruning …

Aneurysmal subarachnoid hemorrhage (SAH) can lead to devastating outcomes including
vasospasm, cognitive decline, and even death. Currently, treatment options are limited for …

Brain injury in premature infants is of enormous public health importance because of the
large number of such infants who survive with serious neurodevelopmental disability …

This review presents a brief overview of the γ-aminobutyric acid (GABA) system in the
developing and mature central nervous system (CNS) and its potential connections to …

With advances in neonatal care, preterm neonates are surviving with an evolving
constellation of motor and cognitive disabilities that appear to be related to widespread …

Objective: The major form of magnetic resonance imaging–defined white matter injury (WMI)
comprises diffuse lesions where the burden of small necrotic foci (microscopic necrosis) is …

Brain injury in the premature infant, a problem of enormous importance, is associated with a
high risk of neurodevelopmental disability. The major type of injury involves cerebral white …