Regulatory role of short-chain fatty acids in inflammatory bowel disease

Z Zhang, H Zhang, T Chen, L Shi, D Wang… - Cell Communication and …, 2022 - Springer
Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory disorders of
the gastrointestinal tract. Accumulating evidence shows that the development of IBD is …

Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids

CH Kim - Cellular & molecular immunology, 2021 - nature.com
A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by
commensal bacteria play essential roles in balancing the immune system. DF, considered …

B vitamins and their role in immune regulation and cancer

CT Peterson, DA Rodionov, AL Osterman, SN Peterson - Nutrients, 2020 - mdpi.com
B group vitamins represent essential micronutrients for myriad metabolic and regulatory
processes required for human health, serving as cofactors used by hundreds of enzymes …

[HTML][HTML] Pro-and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

M Li, BCAM Van Esch, GTM Wagenaar… - European journal of …, 2018 - Elsevier
In the gastro-intestinal tract, short chain fatty acids (SCFAs) have protective effects on
epithelial cells. However, their effects on inflammatory cytokine production by endothelial …

NAD+ Metabolism in Cardiac Health, Aging, and Disease

M Abdellatif, S Sedej, G Kroemer - Circulation, 2021 - Am Heart Assoc
Nicotinamide adenine dinucleotide (NAD+) is a central metabolite involved in energy and
redox homeostasis as well as in DNA repair and protein deacetylation reactions …

Deficiency of prebiotic fiber and insufficient signaling through gut metabolite-sensing receptors leads to cardiovascular disease

DM Kaye, WA Shihata, HA Jama, K Tsyganov… - Circulation, 2020 - Am Heart Assoc
Background: High blood pressure (BP) continues to be a major, poorly controlled but
modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet …

The enteric network: interactions between the immune and nervous systems of the gut

BB Yoo, SK Mazmanian - Immunity, 2017 - cell.com
Interactions between the nervous and immune systems enable the gut to respond to the
variety of dietary products that it absorbs, the broad spectrum of pathogens that it …

Effects of extended-release niacin with laropiprant in high-risk patients

HPS2-Thrive Collaborative Group - New England Journal of …, 2014 - Mass Medical Soc
Background Patients with evidence of vascular disease are at increased risk for subsequent
vascular events despite effective use of statins to lower the low-density lipoprotein (LDL) …

[HTML][HTML] Diet, metabolites, and “western-lifestyle” inflammatory diseases

AN Thorburn, L Macia, CR Mackay - Immunity, 2014 - cell.com
One explanation for the increased incidence of allergies, asthma, and even some
autoimmune diseases has been the hygiene hypothesis. However, recent studies also …

Exploring the immune-boosting functions of vitamins and minerals as nutritional food bioactive compounds: A comprehensive review

S Mitra, S Paul, S Roy, H Sutradhar, T Bin Emran… - Molecules, 2022 - mdpi.com
Food components have long been recognized to play a fundamental role in the growth and
development of the human body, conferring protective functionalities against foreign matter …