For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …

Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Background Malaria elimination requires interruption of the highly efficient transmission of
Plasmodium parasites by mosquitoes. TB31F is a humanised monoclonal antibody that …

De novo peptide sequencing is the key technology for finding novel peptides from mass
spectra. The overall quality of sequencing results depends on the de novo peptide …

Plasmodium parasites have a complex life cycle alternating between a mosquito and a
vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium …

Obligate intracellular malaria parasites reside within a vacuolar compartment generated
during invasion which is the principal interface between pathogen and host. To subvert their …

Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …

Plasmodium falciparum (Pf) is a major cause of human malaria and is transmitted by
infected Anopheles mosquitoes. The initial asymptomatic infection is characterized by …

An essential step in the life cycle of malaria parasites is their egress from hepatocytes, which
enables the transition from the asymptomatic liver stage to the pathogenic blood stage of …

Malaria parasites alter multiple properties of the host erythrocyte by exporting proteins into
the host cell. Many exported proteins contain a five-amino acid motif called the Plasmodium …