The transcriptional repressor REST (Repressor Element-1 Silencing Transcription factor) is
a key modulator of the neuronal epigenome and targets genes involved in neuronal …

RE-1 silencing transcription factor (REST)(known also as NRSF) is a well-known
transcription repressor whose strong decrease induces the distinction of neurons with …

Adult central nervous system (CNS) axons fail to regenerate after injury, and master
regulators of the regenerative program remain to be identified. We analyzed the …

Retinal degeneration is a main class of ocular diseases. So far, retinal progenitor cell (RPC)
transplantation has been the most potential therapy for it, in which promoting RPCs neuronal …

The cochlea is an important sensory organ for both balance and sound perception, and the
formation of the cochlea is a complex developmental process. The development of the …

Retinoic acids (RAs) are the most successful therapeutics for cancer differentiation therapy
used in high-risk neuroblastoma (NB) maintenance therapy but are limited in effectiveness …

The hazards posed by blue light to human eyes are attracting significant attention owing to
increasing exposure to electronic devices as well as artificial illumination. Therefore, in this …

Background and objective Retinoic acid is a metabolite of vitamin A that is necessary to
maintain health in human and most of the other vertebrates. MicroRNAs (miR or miRNAs) …

MicroRNAs have a vital effect on the differentiation of many types of progenitor cells. Recent
studies have suggested that miR-17 plays an important role in the differentiation process of …

Retinal progenitor cells (RPCs) transplantation has become a promising therapy for retinal
degeneration, which is a major kind of ocular diseases causing blindness. Since RPCs have …