A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Nanomaterial-based microfluidic systems for cancer biomarker detection: recent applications and future perspectives

Y Xiang, C Hu, G Wu, S Xu, Y Li - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Detecting cancer biomarkers (eg, circulating tumor cells, extracellular vehicles, nucleic
acids, and protein biomarkers) is vital for risk assessment and early diagnosis. Nanomaterial …

Microfluidic-based technologies for CTC isolation: a review of 10 years of intense efforts towards liquid biopsy

L Descamps, D Le Roy, AL Deman - International Journal of Molecular …, 2022 - mdpi.com
The selection of circulating tumor cells (CTCs) directly from blood as a real-time liquid
biopsy has received increasing attention over the past ten years, and further analysis of …

Advances in technical assessment of spiral inertial microfluidic devices toward bioparticle separation and profiling: A critical review

M Bagi, F Amjad, SM Ghoreishian… - BioChip Journal, 2024 - Springer
Separation of micro-and nano-sized bioparticles is essential for efficient diagnostics,
chemical and biological analyses, drug development, food and chemical processing, and …

Recent advances in microfluidic platforms applied in cancer metastasis: Circulating tumor cells'(CTCs) isolation and tumor‐on‐a‐chip

Z Lin, G Luo, W Du, T Kong, C Liu, Z Liu - Small, 2020 - Wiley Online Library
Cancer remains the leading cause of death worldwide despite the enormous efforts that are
made in the development of cancer biology and anticancer therapeutic treatment …

Recent progress of inertial microfluidic-based cell separation

X Xu, X Huang, J Sun, R Wang, J Yao, W Han, M Wei… - Analyst, 2021 - pubs.rsc.org
Cell separation has consistently been a pivotal technology of sample preparation in
biomedical research. Compared with conventional bulky cell separation technologies …

Recent advances in microfluidic platform for physical and immunological detection and capture of circulating tumor cells

MP Bhat, V Thendral, UT Uthappa, KH Lee, M Kigga… - Biosensors, 2022 - mdpi.com
CTCs (circulating tumor cells) are well-known for their use in clinical trials for tumor
diagnosis. Capturing and isolating these CTCs from whole blood samples has enormous …

High-efficiency isolation and rapid identification of heterogeneous circulating tumor cells (CTCs) using dual-antibody-modified fluorescent-magnetic nanoparticles

Z Wang, N Sun, H Liu, C Chen, P Ding… - … applied materials & …, 2019 - ACS Publications
Extreme rarity and inherent heterogeneity of circulating tumor cells (CTCs) result in a
tremendous challenge for the CTC isolation from patient blood samples with high efficiency …

A smartphone-based biomedical sensory system

W Zhao, S Tian, L Huang, K Liu, L Dong, J Guo - Analyst, 2020 - pubs.rsc.org
Disease diagnostics, food safety monitoring and environmental quality monitoring are the
key means to safeguard human health. However, conventional detection devices for health …

[HTML][HTML] Advances in isolation and detection of circulating tumor cells based on microfluidics

D Zou, D Cui - Cancer biology & medicine, 2018 - ncbi.nlm.nih.gov
Circulating tumor cells (CTCs) are the cancer cells that circulate in the peripheral blood after
escaping from the original or metastatic tumors. CTCs could be used as non-invasive source …