A common feature of cancer cells is their ability to rewire their metabolism to sustain the
production of ATP and macromolecules needed for cell growth, division and survival. In …

Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Chronic inflammation is a known risk factor for gastrointestinal cancer. The evidence that
nonsteroidal anti-inflammatory drugs suppress the incidence, growth, and metastasis of …

γδ T cells have recently gained considerable attention as an attractive tool for cancer
adoptive immunotherapy due to their potent anti-tumor activity and unique role in …

Chronic inflammation is a risk factor for gastrointestinal cancer and other diseases. Most
studies have focused on cytokines and chemokines as mediators connecting chronic …

Oncogenic transformation is associated with profound changes in cellular metabolism, but
whether tracking these can improve disease stratification or influence therapy decision …

ABSTRACT γδ T cells usually infiltrate many different types of cancer, but it is unclear
whether they inhibit or promote tumor progression. Moreover, properties of tumor-infiltrating …

The lymphocyte function-associated antigen-1 (LFA-1)(also known as CD11a/CD18 and
αLβ2), is just one of many integrins in the human body, but its significance is derived from its …

Cancer immunotherapy is a field of interest in the recent treatment approaches against
cancer cells, as it could use the assets of the host's immune system against the invading …

Metabolic engagement is intrinsic to immune cell function. Prostaglandin E2 (PGE2) has
been shown to modulate macrophage activation, yet how PGE2 might affect metabolism is …