Involvement of STAT5 in Oncogenesis

CE Halim, S Deng, MS Ong, CT Yap - Biomedicines, 2020 - mdpi.com
Signal transducer and activator of transcription (STAT) proteins, and in particular STAT3,
have been established as heavily implicated in cancer. Recently, the involvement of STAT5 …

STAT5-interacting proteins: a synopsis of proteins that regulate STAT5 activity

AA Able, JA Burrell, JM Stephens - Biology, 2017 - mdpi.com
Signal Transducers and Activators of Transcription (STATs) are key components of the
JAK/STAT pathway. Of the seven STATs, STAT5A and STAT5B are of particular interest for …

SAPCD2 promotes neuroblastoma progression by altering the subcellular distribution of E2F7

ZM Zhang, HB Cao, ZH Li, R Zhuo, YF Tao, XL Li… - Cell death & …, 2022 - nature.com
Recent studies uncovered the emerging roles of SAPCD2 (suppressor anaphase-promoting
complex domain containing 2) in several types of human cancer. However, the functions and …

Association of DCBLD2 upregulation with tumor progression and poor survival in colorectal cancer

J He, H Huang, Y Du, D Peng, Y Zhou, Y Li, H Wang… - Cellular Oncology, 2020 - Springer
Purpose DCBLD2 expression dysregulation has been reported in several types of human
cancer. As yet, however, the role of DCBLD2 in colorectal cancer (CRC) is not known …

Long noncoding RNA PXN‐AS1‐L promotes the malignancy of nasopharyngeal carcinoma cells via upregulation of SAPCD2

X Jia, P Niu, C Xie, H Liu - Cancer medicine, 2019 - Wiley Online Library
Accumulating evidences highlight the critical roles of long noncoding RNAs (lncRNAs) in a
variety of cancers. LncRNA PXN‐AS1‐L was previously shown to exert oncogenic roles in …

Overexpression of SAPCD2 correlates with proliferation and invasion of colorectal carcinoma cells

Y Luo, L Wang, W Ran, G Li, Y Xiao, X Wang… - Cancer Cell …, 2020 - Springer
Background Suppressor anaphase-promoting complex domain containing 2 (SAPCD2) is a
novel gene playing important roles in the initiation, invasion, and metastasis of several …

C9orf140, a novel Axin1-interacting protein, mediates the negative feedback loop of Wnt/β-catenin signaling

J Jiang, S Tang, J Xia, J Wen, S Chen, X Shu… - Oncogene, 2018 - nature.com
Wnt/β-catenin signaling activity is maintained in homeostasis by an expanding list of
molecular determinants. However, the molecular components and the regulatory …

Method of treating with a peptide

M Andrea, T Weinschenk, O Schoor, J Fritsche… - US Patent …, 2020 - Google Patents
2019-11-06 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers

M Andrea, T Weinschenk, O Schoor, J Fritsche… - US Patent …, 2020 - Google Patents
2019-12-13 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers

M Andrea, T Weinschenk, O Schoor, J Fritsche… - US Patent …, 2020 - Google Patents
2018-10-23 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …