Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta …

H Yao, A Zhang, D Li, Y Wu, CZ Wang, JY Wan… - bmj, 2024 - bmj.com
Objective To evaluate the comparative efficacy and safety of glucagon-like peptide-1
receptor agonists (GLP-1RAs) on glycaemic control, body weight, and lipid profile in adults …

Prevention of cardiorenal complications in people with type 2 diabetes and obesity

DJ Drucker - Cell Metabolism, 2024 - cell.com
Traditional approaches to prevention of the complications of type 2 diabetes (T2D) and
obesity have focused on reduction of blood glucose and body weight. The development of …

Socioeconomic aspects of incretin-based therapy

T Karagiannis, E Bekiari, A Tsapas - Diabetologia, 2023 - Springer
Incretin-based therapies, particularly glucagon-like peptide-1 receptor agonists (GLP-1
RAs), have demonstrated cardiovascular benefits in people with type 2 diabetes. However …

Effect of tirzepatide on albuminuria levels and renal function in patients with type 2 diabetes mellitus: A systematic review and multilevel meta‐analysis

P Karakasis, D Patoulias, N Fragakis… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim The present systematic review aimed to summarize the available evidence from
published randomized controlled trials (RCTs) regarding the effect of tirzepatide on …

Do SGLT2 inhibitors and GLP-1 receptor agonists modulate differently the risk of stroke? Discordance between randomised controlled trials and observational studies

AJ Scheen - Diabetes & Metabolism, 2023 - Elsevier
Stroke represents a major burden in patients with type 2 diabetes, yet this cerebrovascular
complication has been less carefully investigated than the risk of cardiovascular mortality …

Sodium–glucose co-transporter-2 inhibitors for hospitalised patients with COVID-19: a prospective meta-analysis of randomised trials

C Vale, PJ Godolphin, D Fisher, PW Horby… - The Lancet Diabetes & …, 2024 - thelancet.com
Background Sodium–glucose co-transporter-2 (SGLT2) inhibitors have been proposed as a
potential treatment for adults hospitalised with COVID-19, due to their potential anti …

Pharmacotherapy before and after bariatric surgery

K Alabduljabbar, CW le Roux - Metabolism, 2023 - Elsevier
Diabetes is a chronic disease that affects a vast number of individuals globally, and without
optimal treatment, can lead to significant health complications. Moreover, obesity is another …

Drug Therapies for diabetes

R Weinberg Sibony, O Segev, S Dor, I Raz - International Journal of …, 2023 - mdpi.com
The treatment of type 2 diabetes (T2D) necessitates a multifaceted approach that combines
behavioral and pharmacological interventions to mitigate complications and sustain a high …

GLP-1 receptor agonists and risk for cirrhosis and related complications in patients with metabolic dysfunction-Associated Steatotic Liver Disease

F Kanwal, JR Kramer, L Li, YX Yang, Y Cao… - JAMA internal …, 2024 - jamanetwork.com
Importance Metabolic dysfunction-associated steatotic liver disease (MASLD) is an
increasing cause of cirrhosis. Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are …

Gut microbiota interventions in type 2 diabetes mellitus: An umbrella review of glycemic indices

MH Keivanlou, E Amini-Salehi, N Sattari… - Diabetes & Metabolic …, 2024 - Elsevier
Background We aimed to explore how probiotics, prebiotics, or synbiotics impact glycemic
indices in patients with diabetes mellitus. Method A comprehensive search was conducted …