Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …

People worldwide are living longer, and it is estimated that by 2050, the proportion of the
world's population over 60 years of age will nearly double. Natural lung aging is associated …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disorder of unknown origin and
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …

Fibrosis is the final pathological outcome and major cause of morbidity and mortality in many
common and chronic inflammatory, immune-mediated, and metabolic diseases. Despite the …

Aging is an inevitable and complex natural phenomenon due to the increase in age. Cellular
senescence means a non-proliferative but viable cellular physiological state. It is the basis of …

The glucose transporter family (GLUT) consists of fourteen members. It is responsible for
glucose homeostasis and glucose transport from the extracellular space to the cell …

CTGF is upregulated in patients with idiopathic pulmonary fibrosis (IPF), characterized by
the deposition of a pathological extracellular matrix (ECM). Additionally, many omics studies …

At present, the etiology of idiopathic pulmonary fibrosis (IPF) remains elusive. Over the past
two decades, however, researchers have identified and described the underlying processes …

AMP-activated protein kinase (AMPK) is a protein kinase that plays versatile roles in
response to a variety of physiological stresses, including glucose deprivation, hypoxia, and …

Glutaminolysis is the metabolic process of glutamine, aberration of which has been
implicated in several pathogeneses. Although we and others recently found a diversity of …