Highlights in heart failure

D Tomasoni, M Adamo, CM Lombardi… - ESC heart …, 2019 - Wiley Online Library
Heart failure (HF) remains a major cause of mortality, morbidity, and poor quality of life. It is
an area of active research. This article is aimed to give an update on recent advances in all …

Transthyretin cardiac amyloidosis: an update on diagnosis and treatment

H Yamamoto, T Yokochi - ESC heart failure, 2019 - Wiley Online Library
Transthyretin cardiac amyloidosis (ATTR‐CA) demonstrates progressive, potentially fatal,
and infiltrative cardiomyopathy caused by extracellular deposition of transthyretin‐derived …

Carpal tunnel syndrome in cardiac amyloidosis: implications for early diagnosis and prognostic role across the spectrum of aetiologies

A Milandri, A Farioli, C Gagliardi… - European journal of …, 2020 - Wiley Online Library
Aims We aimed to assess carpal tunnel syndrome (CTS) prevalence in transthyretin (TTR)‐
related and light‐chain amyloidosis (AL), comparing it to the general population, adjusted for …

Heart failure in the last year: progress and perspective

D Tomasoni, M Adamo, MS Anker… - ESC heart …, 2020 - Wiley Online Library
Research about heart failure (HF) has made major progress in the last years. We give here
an update on the most recent findings. Landmark trials have established new treatments for …

Efficacy of tafamidis in patients with hereditary and wild-type transthyretin amyloid cardiomyopathy: further analyses from ATTR-ACT

C Rapezzi, P Elliott, T Damy, J Nativi-Nicolau, JL Berk… - Heart Failure, 2021 - jacc.org
Objectives Tafamidis is an effective treatment for transthyretin amyloid cardiomyopathy
(ATTR-CM), this study aimed to determine whether there is a differential effect between …

Prevalence and clinical outcomes of transthyretin amyloidosis: a systematic review and meta‐analysis

AS Antonopoulos, I Panagiotopoulos… - European Journal of …, 2022 - Wiley Online Library
Aim Systematic evidence on the prevalence and clinical outcome of transthyretin
amyloidosis (ATTR) is missing. We explored:(i) the prevalence of cardiac amyloidosis in …

ATTRv amyloidosis Italian Registry: clinical and epidemiological data

M Russo, L Obici, I Bartolomei, F Cappelli, M Luigetti… - Amyloid, 2020 - Taylor & Francis
Introduction ATTRv amyloidosis is worldwide spread with endemic foci in Portugal and
Sweden, Japan, Brazil, Maiorca, and Cyprus. A national Registry was developed to …

Prevalence and Outcomes of p.Val142Ile TTR Amyloidosis Cardiomyopathy: A Systematic Review

P Chandrashekar, L Alhuneafat… - Circulation: Genomic …, 2021 - Am Heart Assoc
Background: The p. Val142Ile variant, predominantly found among people of African
descent, is the most common cause of variant transthyretin amyloidosis and carriers …

Effectiveness and safety of oral anticoagulants in cardiac amyloidosis: lights and shadows

D Di Lisi, L Di Caccamo, G Damerino… - Current Problems in …, 2023 - Elsevier
Cardiac amyloidosis (CA) is an infiltrative cardiomyopathy characterized by extracellular
deposition of mis-folded proteins called amyloid. Cardiac complications of CA are several …

Use of drugs for ATTRv amyloidosis in the real world: how therapy is changing survival in a non-endemic area

M Russo, L Gentile, V Di Stefano, G Di Bella, F Minutoli… - Brain Sciences, 2021 - mdpi.com
Background: Over the past decade, three new drugs have been approved for the treatment
of hereditary amyloid transthyretin (ATTRv) polyneuropathy. The aim of this work was to …