Nerve terminals are specific sites of action of a very large number of toxins produced by
many different organisms. The mechanism of action of three groups of presynaptic …

Neurexins and neuroligins are emerging as central organizing molecules for excitatory
glutamatergic and inhibitory GABAergic synapses in mammalian brain. They function as cell …

The endogenous cannabinoid receptor agonist anandamide is a powerful vasodilator of
isolated vascular preparations,,, but its mechanism of action is unclear. Here we show that …

Synapses are specialized intercellular junctions in which cell adhesion molecules connect
the presynaptic machinery for neurotransmitter release to the postsynaptic machinery for …

Elucidation of molecular mechanisms that regulate synapse formation is required for the
understanding of neural wiring, higher brain functions, and mental disorders. Despite the …

Autism is a neurodevelopmental disorder of complex etiology in which genetic factors play a
major role. We have implicated the neurexin 1 (NRXN1) gene in two independent subjects …

It was long ago that group analysis of differential equations became a powerful tool for
studying nonlinear equations and boundary value problems. This analysis was especially …

The neurexin family of cell adhesion proteins consists of three members in vertebrates and
has homologs in several invertebrate species. In mammals, each neurexin gene encodes an …

Neurexins are neuron-specific vertebrate proteins with hundreds of differentially spliced
isoforms that may function in synapse organization. We now show that Drosophila …

Spider venoms represent an incredible source of biologically active substances which
selectively target a variety of vital physiological functions in both insects and mammals …