In-vivo corneal confocal microscopy: Imaging analysis, biological insights and future directions

JCB Chiang, M Roy, J Kim, M Markoulli… - Communications …, 2023 - nature.com
In-vivo corneal confocal microscopy is a powerful imaging technique which provides
clinicians and researcher with the capabilities to observe microstructures at the ocular …

The global and regional burden of diabetic peripheral neuropathy

MG Savelieff, MA Elafros, V Viswanathan… - Nature Reviews …, 2024 - nature.com
Diabetic peripheral neuropathy (DPN) is length-dependent peripheral nerve damage arising
as a complication of type 1 or type 2 diabetes in up to 50% of patients. DPN poses a …

Sustained corneal nerve loss predicts the development of diabetic neuropathy in type 2 diabetes

G Ponirakis, I Al-Janahi, E Elgassim… - Frontiers in …, 2024 - frontiersin.org
Introduction This study was undertaken to investigate whether sustained rather than a single
measure of corneal nerve loss was associated with the onset of diabetic peripheral …

Continuous glucose monitoring reveals a novel association between duration and severity of hypoglycemia, and small nerve fiber injury in patients with diabetes

H Gad, E Elgassim, I Mohammed… - Endocrine …, 2022 - ec.bioscientifica.com
Objective: Continuous glucose monitoring has revealed that glycemic variability and low
time in range are associated with albuminuria and retinopathy. We have investigated the …

Glucose‐lowering medication associated with weight loss may limit the progression of diabetic neuropathy in type 2 diabetes

G Ponirakis, I Al‐Janahi, E Elgassim… - Journal of the …, 2024 - Wiley Online Library
Aim Obesity is a major risk factor for diabetic peripheral neuropathy (DPN) in type 2 diabetes
(T2D). This study investigated the effect of glucose lowering medication associated with …

Quantitative sensory testing defines the trajectory of sensory neuropathy after severe COVID-19

G Ponirakis, A Odriozola, L Ortega, L Martinez… - Diabetes Research and …, 2024 - Elsevier
Aims To assess sensory neuropathy development after severe COVID-19. Methods Patients
with severe COVID-19 underwent assessment of neuropathic symptoms, tendon reflexes …

[HTML][HTML] Diet and exercise are a fundamental part of comprehensive care for type 2 diabetes

YK Yeh, FS Yen, CM Hwu - Journal of Diabetes Investigation, 2023 - ncbi.nlm.nih.gov
In this modern era, numerous innovative glucose-lowering medications have emerged,
leading to a wide range of treatment options for type 2 diabetes mellitus. While …

Corneal confocal microscopy detects early nerve regeneration after pharmacological and surgical interventions: Systematic review and meta‐analysis

H Gad, E Elgassim, A Lebbe… - Journal of the …, 2024 - Wiley Online Library
Corneal confocal microscopy (CCM) is an ophthalmic imaging technique that enables the
identification of corneal nerve fibre degeneration and regeneration. To undertake a …

How does the clinical practice of Aotearoa New Zealand podiatrists align with international guidelines for the prevention of diabetes‐related foot disease? A cross …

H Jepson, PA Lazzarini, M Garrett… - Journal of Foot and …, 2023 - Wiley Online Library
Background Given the importance of preventive care for the lower limb in people with
diabetes, and the absence of local guidelines in Aotearoa New Zealand (NZ), the aim of this …

Limitations of glycated albumin standardization when applied to the assessment of diabetes patients

E Lenters-Westra, SL Atkin, ES Kilpatrick… - Clinical Chemistry and …, 2024 - degruyter.com
Objectives Glycated albumin (GA) has potential value in the management of people with
diabetes; however, to draw meaningful conclusions between clinical studies it is important …