Transforming growth factor-β1 to the bone

K Janssens, P Ten Dijke, S Janssens… - Endocrine …, 2005 - academic.oup.com
TGF-β1 is a ubiquitous growth factor that is implicated in the control of proliferation,
migration, differentiation, and survival of many different cell types. It influences such diverse …

Calcium phosphate cements as bone drug delivery systems: a review

MP Ginebra, T Traykova, JA Planell - Journal of controlled release, 2006 - Elsevier
Since calcium phosphate cements were proposed, several formulations have been
developed, some of them commercialised, and they have proven to be very efficient bone …

Organic–inorganic surface modifications for titanium implant surfaces

LT de Jonge, SCG Leeuwenburgh, JGC Wolke… - Pharmaceutical …, 2008 - Springer
This paper reviews current physicochemical and biochemical coating techniques that are
investigated to enhance bone regeneration at the interface of titanium implant materials. By …

Use of recombinant human bone morphogenetic protein-2 to enhance tendon healing in a bone tunnel

SA Rodeo, K Suzuki, X Deng… - … American journal of …, 1999 - journals.sagepub.com
This study examines the hypothesis that recombinant human bone morphogenetic protein-2
can enhance bone ingrowth into a tendon graft placed into a bone tunnel. We transplanted …

Retention of in vitro and in vivo BMP-2 bioactivities in sustained delivery vehicles for bone tissue engineering

DHR Kempen, L Lu, TE Hefferan, LB Creemers… - Biomaterials, 2008 - Elsevier
In this study, we investigated the in vitro and in vivo biological activities of bone
morphogenetic protein 2 (BMP-2) released from four sustained delivery vehicles for bone …

Platelet-rich plasma enhances human osteoblast-like cell proliferation and differentiation

T Kanno, T Takahashi, T Tsujisawa, W Ariyoshi… - Journal of Oral and …, 2005 - Elsevier
PURPOSE: Platelet-rich plasma (PRP) is widely used to promote tissue healing. However,
there is no concrete evidence for the biological effects of PRP. This study evaluated the …

Calcium phosphate cements: competitive drug carriers for the musculoskeletal system?

MP Ginebra, T Traykova, JA Planell - Biomaterials, 2006 - Elsevier
This paper attempts to provide an insight in the application of calcium phosphate cements
(CPC) in the field of drug delivery devices for the musculoskeletal system. Their ability to set …

Growth factor-loaded scaffolds for bone engineering

JA Jansen, JWM Vehof, PQ Ruhe… - Journal of Controlled …, 2005 - Elsevier
The objective of the study presented here was to investigate the bone inductive properties
as well as release kinetics of rhTGF-β1-and rhBMP-2-loaded Ti-fiber mesh and CaP cement …

Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants in cranial defects in rabbits

PQ Ruhé, HC Kroese-Deutman, JGC Wolke… - Biomaterials, 2004 - Elsevier
In this study, the osteoinductive properties of porous calcium phosphate (Ca-P) cement
loaded with bone morphogenetic protein 2 (rhBMP-2) were evaluated and compared with …

Transforming growth factor beta in fracture repair.

MPG Bostrom, P Asnis - Clinical Orthopaedics and Related …, 1998 - journals.lww.com
Transforming growth factor betas are a group of polypeptide growth factors that have a wide
range of activities in the musculoskeletal and immunological systems. They are thought to …