3d transition metals for C–H activation

P Gandeepan, T Müller, D Zell, G Cera… - Chemical …, 2018 - ACS Publications
C–H activation has surfaced as an increasingly powerful tool for molecular sciences, with
notable applications to material sciences, crop protection, drug discovery, and …

Cation− π interactions in organic synthesis

S Yamada - Chemical reviews, 2018 - ACS Publications
The cation− π interaction is an attractive noncovalent interaction between a cation and a π
system. Due to the stronger interaction energy than those of the other π interactions, such as …

Recent advances in the diversification of chromones and flavones by direct CH bond activation or functionalization

S Tian, T Luo, Y Zhu, JP Wan - Chinese Chemical Letters, 2020 - Elsevier
Chromone and flavone are both central backbones of natural products and clinical
medicines. Synthesis of diversely functionalized chromones and flavones constitutes …

Synthetic protocols for aromatic nitration: A review

SS Patel, DB Patel, HD Patel - ChemistrySelect, 2021 - Wiley Online Library
Nitration of aromatic compounds represents a powerful and widely used transformation that
allows introducing nitro group into aromatic systems. New synthetic strategies for aromatic …

Recent advances in transition metal-catalyzed C (sp 2)–H nitration

LR Song, Z Fan, A Zhang - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
Nitroaromatic compounds play an important role in organic synthesis, medicinal chemistry
and chemical industry. Among the recently reported synthetic methods to access …

Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the Protein–RNA interaction of LIN28–let-7

GL Goebel, L Hohnen, L Borgelt, P Hommen… - European journal of …, 2022 - Elsevier
Inhibition of the RNA-binding protein LIN28 and disruption of the protein–RNA interaction of
LIN28–let-7 with small molecules holds great potential to develop new anticancer …

Overcoming back electron transfer in the electron donor–acceptor complex-mediated visible light-driven generation of α-aminoalkyl radicals from secondary anilines

A Runemark, H Sundén - The Journal of Organic Chemistry, 2022 - ACS Publications
An additive-free, visible light-driven annulation between N-aryl amino acids and maleimide
to form tetrahydroquinolines (THQs) is disclosed. Photochemical activation of an electron …

Iron promoted C3–H nitration of 2 H-indazole: direct access to 3-nitro-2 H-indazoles

A Murugan, KR Gorantla, BS Mallik… - Organic & Biomolecular …, 2018 - pubs.rsc.org
An efficient C3–H functionalization of indazole has been demonstrated. Notably, this method
involves chelation-free radical C–H nitration on 2H-indazole. The radical mechanism was …

Copper-mediated domino C–H iodination and nitration of indoles

D Tu, J Luo, C Jiang - Chemical Communications, 2018 - pubs.rsc.org
An efficient and cost-effective copper-mediated aerobic oxidative C–H iodination and
nitration of indoles via double C–H functionalization is reported. The domino process …

NaNO2/K2S2O8‐mediated Selective Radical Nitration/Nitrosation of Indoles: Efficient Approach to 3‐Nitro‐ and 3‐Nitrosoindoles

A Shoberu, CK Li, ZK Tao, GY Zhang… - Advanced Synthesis & …, 2019 - Wiley Online Library
A mild and selective radical nitration/nitrosation of indoles with NaNO2 using K2S2O8 as
oxidant is developed. Free (NH)‐indoles and N‐methyl indoles furnished 3‐nitro‐and 3 …