Progesterone and neuroprotection

M Singh, C Su - Hormones and behavior, 2013 - Elsevier
This article is part of a Special Issue" Hormones & Neurotrauma". Numerous studies aimed
at identifying the role of estrogen on the brain have used the ovariectomized rodent as the …

Membrane progesterone receptors: evidence for neuroprotective, neurosteroid signaling and neuroendocrine functions in neuronal cells

P Thomas, Y Pang - Neuroendocrinology, 2012 - karger.com
Membrane progesterone receptors (mPRs) are novel G protein-coupled receptors belonging
to the progestin and adipoQ receptor family (PAQR) that mediate a variety of rapid cell …

Progesterone-mediated non-classical signaling

D Garg, SSM Ng, KM Baig, P Driggers… - Trends in Endocrinology & …, 2017 - cell.com
Progesterone is essential for pregnancy maintenance and menstrual cycle regulation.
Hormone action has been primarily ascribed to the well-characterized classical signaling …

Membrane progesterone receptor expression in mammalian tissues: a review of regulation and physiological implications

GE Dressing, JE Goldberg, NJ Charles… - Steroids, 2011 - Elsevier
The recent discovery of a novel, membrane localized progestin receptor (mPR) unrelated to
the classical progesterone receptor (PR) in fishes and its subsequent identification in …

Rapid steroid hormone actions initiated at the cell surface and the receptors that mediate them with an emphasis on recent progress in fish models

P Thomas - General and comparative endocrinology, 2012 - Elsevier
In addition to the classic genomic mechanism of steroid action mediated by activation of
intracellular nuclear receptors, there is now extensive evidence that steroids also activate …

Distribution of membrane progesterone receptor alpha in the male mouse and rat brain and its regulation after traumatic brain injury

D Meffre, F Labombarda, B Delespierre, A Chastre… - Neuroscience, 2013 - Elsevier
Progesterone has been shown to exert pleiotropic actions in the brain of both male and
females. In particular, after traumatic brain injury (TBI), progesterone has important …

Selective progesterone receptor modulators (SPRMs): progesterone receptor action, mode of action on the endometrium and treatment options in gynecological …

A Wagenfeld, PTK Saunders, L Whitaker… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: The progesterone receptor plays an essential role in uterine physiology and
reproduction. Selective progesterone receptor modulators (SPRMs) have emerged as a …

Neuroprotection by gonadal steroid hormones in acute brain damage requires cooperation with astroglia and microglia

S Johann, C Beyer - The Journal of steroid biochemistry and molecular …, 2013 - Elsevier
The neuroactive steroids 17β-estradiol and progesterone control a broad spectrum of neural
functions. Besides their roles in the regulation of classical neuroendocrine loops, they …

Progesterone signaling mechanisms in brain and behavior

SK Mani, MG Oyola - Frontiers in Endocrinology, 2012 - frontiersin.org
Steroid hormone, progesterone, modulates neuroendocrine functions in the central nervous
system resulting in alterations in physiology and behavior. These neuronal effects are …

Distribution and estrogen regulation of membrane progesterone receptor-β in the female rat brain

DG Zuloaga, SL Yahn, Y Pang, AM Quihuis… - …, 2012 - academic.oup.com
Although several studies have reported the localization of membrane progesterone (P4)
receptors (mPR) in various tissues, few have attempted to describe the distribution and …