Hypertension is associated with immune cells activation and their migration into the kidney,
vasculature, heart and brain. These inflammatory mechanisms are critical for blood pressure …

One of the main features of the immune response to M. Tuberculosis is the formation of an
organized structure called granuloma. It consists mainly in the recruitment at the infectious …

Although the classical antibiotic spectinomycin is a potent bacterial protein synthesis
inhibitor, poor antimycobacterial activity limits its clinical application for treating tuberculosis …

XCL1, a C class chemokine also known as lymphotactin, is produced by T, NK, and NKT
cells during infectious and inflammatory responses, whereas XCR1, the receptor of XCL1, is …

Abnormal tumor vasculature impairs T lymphocyte adhesion to endothelial cells and
lymphocyte extravasation into neoplastic tissues, limiting the therapeutic potential of both …

T cells are potent at eliminating pathogens and playing a crucial role in the adaptive immune
response. T cell receptor (TCR) convergence describes T cells that share identical TCRs …

T cells are important in the pathogenesis of acute kidney injury (AKI), and TCR+ CD4-CD8-
(double negative-DN) are T cells that have regulatory properties. However, there is limited …

Anti-TNF immunotherapy has revolutionized the treatment of some inflammatory diseases,
such as RA. However, a major concern is that patients receiving this therapy have an …

RNA interference (RNAi) is a potent and specific post-transcriptional gene silencing process.
Since its discovery, tremendous efforts have been made to translate RNAi technology into …

Genetically resistant or susceptible chickens to Marek's disease (MD) have been widely
used models to identify the molecular determinants of these phenotypes. However, these …