Prognostic and predictive biomarkers for immunotherapy in advanced renal cell carcinoma

M Rosellini, A Marchetti, V Mollica, A Rizzo… - Nature Reviews …, 2023 - nature.com
The therapeutic algorithm of renal cell carcinoma has been revolutionized by the approval of
immunotherapy agents by regulatory agencies. However, objective and durable responses …

Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD

IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …

Portable smartphone platform based on a single dual-emissive ratiometric fluorescent probe for visual detection of isopropanol in exhaled breath

F Yang, D Lin, L Pan, J Zhu, J Shen, L Yang… - Analytical …, 2021 - ACS Publications
The components in the exhaled breath have been confirmed to be related to certain
diseases, especially studies have shown that isopropanol (IPA) might be closely associated …

Smelling the disease: Diagnostic potential of breath analysis

A Sharma, R Kumar, P Varadwaj - Molecular Diagnosis & Therapy, 2023 - Springer
Breath analysis is a relatively recent field of research with much promise in scientific and
clinical studies. Breath contains endogenously produced volatile organic components …

VOC breath biomarkers in lung cancer

Y Saalberg, M Wolff - Clinica Chimica Acta, 2016 - Elsevier
This review provides an overview of volatile organic compounds (VOCs) which are
considered lung cancer biomarkers for diagnostic breath analysis. It includes results of …

[HTML][HTML] Breath analysis as a potential and non-invasive frontier in disease diagnosis: an overview

J Pereira, P Porto-Figueira, C Cavaco, K Taunk… - Metabolites, 2015 - mdpi.com
Currently, a small number of diseases, particularly cardiovascular (CVDs), oncologic (ODs),
neurodegenerative (NDDs), chronic respiratory diseases, as well as diabetes, form a severe …

Diagnostic performance of electronic noses in cancer diagnoses using exhaled breath: A systematic review and meta-analysis

MHMC Scheepers, Z Al-Difaie, L Brandts… - JAMA network …, 2022 - jamanetwork.com
Importance There has been a growing interest in the use of electronic noses (e-noses) in
detecting volatile organic compounds in exhaled breath for the diagnosis of cancer …

Diagnosis of COVID-19 by exhaled breath analysis using gas chromatography–mass spectrometry

W Ibrahim, RL Cordell, MJ Wilde… - ERJ open …, 2021 - Eur Respiratory Soc
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic has claimed
over two and a half million lives worldwide so far. Severe acute respiratory syndrome …

The metabolic theory of pulmonary arterial hypertension

R Paulin, ED Michelakis - Circulation research, 2014 - Am Heart Assoc
Numerous molecular abnormalities have been described in pulmonary arterial hypertension
(PAH), complicating the translation of candidate therapies to patients because, typically, 1 …

[HTML][HTML] Metabolomics for the masses: The future of metabolomics in a personalized world

DK Trivedi, KA Hollywood, R Goodacre - New horizons in translational …, 2017 - Elsevier
Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …