Although the basic principles of neocortical development have been known for quite some
time, it is only recently that our understanding of the molecular mechanisms that are involved …

Neuronal migration has been studied extensively for over 30 years in diverse mammalian
species from the mouse to human. The sequence of events that occurs during cortical …

Abstract Mutations in mammalian Lis1 (Pafah1b1) result in neuronal migration defects.
Several lines of evidence suggest that LIS1 participates in pathways regulating microtubule …

CLIP-170 is a plus-end tracking protein which may act as an anticatastrophe factor. It has
been proposed to mediate the association of dynein/dynactin to microtubule (MT) plus ends …

Mutations in the Lis1 gene result in lissencephaly (smooth brain), a debilitating
developmental syndrome caused by the impaired ability of postmitotic neurons to migrate to …

Platelet-activating factor(PAF) is one of the most potent lipid messengers involved in a
variety of physiological events. The acetyl group at the sn-2 position of its glycerol back bone …

Mutations in the LIS1 gene cause lissencephaly, a human neuronal migration disorder. LIS1
binds dynein and the dynein-associated proteins Nde1 (formerly known as NudE), Ndel1 …

This review is dedicated to the memory of Professor Sir Vincent B. Wigglesworth (VW) in
recognition of his many pioneering contributions to insect physiology which, even today …

Platelet-activating factor (PAF) is one of the most potent lipid mediators and is involved in a
variety of physiological events. The acetyl group at the sn-2 position of its glycerol backbone …

Microtubules are cellular components that are required for a variety of essential processes
such as cell motility, mitosis, and intracellular transport. This is possible because of the …