Growth and neurodevelopment of HIV-exposed uninfected children: a conceptual framework

CJ Wedderburn, C Evans, S Yeung, DM Gibb… - Current HIV/AIDS …, 2019 - Springer
Abstract Purpose of Review The population of HIV-exposed uninfected (HEU) children is
expanding rapidly, and over one million HEU infants are born each year globally. Several …

A meta-analysis assessing diarrhea and pneumonia in HIV-exposed uninfected compared with HIV-unexposed uninfected infants and children

AT Brennan, R Bonawitz, CJ Gill, DM Thea… - JAIDS Journal of …, 2019 - journals.lww.com
Objective: Previous studies have demonstrated that HIV-exposed uninfected (HEU) infants
and children experience morbidity and mortality at rates exceeding those of their HIV …

Estimates of the global population of children who are HIV-exposed and uninfected, 2000–18: a modelling study

AL Slogrove, KM Powis, LF Johnson… - The Lancet Global …, 2020 - thelancet.com
Background Children who are HIV-exposed uninfected (HEU) have higher morbidity and
mortality than children who are HIV-unexposed and uninfected despite safer breastfeeding …

Children who are HIV-exposed and uninfected: evidence for action

AJ Prendergast, C Evans - Aids, 2023 - journals.lww.com
Prior to widespread availability of antiretroviral therapy (ART) in sub-Saharan Africa,
children who were HIV-exposed but uninfected (HEU) had increased mortality, morbidity …

Increased infectious-cause hospitalization among infants who are HIV-exposed uninfected compared with HIV-unexposed

K Anderson, E Kalk, HP Madlala, DC Nyemba… - Aids, 2021 - journals.lww.com
Objectives: Increased risk of morbidity and hospitalization has been observed in children
who are HIV-exposed uninfected (HEU) compared with HIV-unexposed uninfected (HUU) …

HIV-exposed-uninfected infants have increased inflammation and monocyte activation

S Dirajlal-Fargo, MM Mussi-Pinhata, A Weinberg, Q Yu… - Aids, 2019 - journals.lww.com
Background: HIV-exposed-uninfected (HEU) infants have increased infectious morbidity and
mortality; little is known about their levels of inflammation and monocyte activation. Methods …

In utero ART exposure and birth and early growth outcomes among HIV-exposed uninfected infants attending immunization services: results from national PMTCT …

V Ramokolo, AE Goga, C Lombard… - Open forum …, 2017 - academic.oup.com
Background Despite the recognized benefit of antiretroviral therapy (ART) for preventing and
treating HIV, some studies have reported adverse birth outcomes with in utero ART …

Neurodevelopment among children exposed to HIV and uninfected in sub‐Saharan Africa

MA Bulterys, I Njuguna, M Mahy… - Journal of the …, 2023 - Wiley Online Library
Introduction The population of 16 million children exposed to HIV and uninfected (CHEU)
under 15 years of age continues to expand rapidly, and the estimated prevalence of CHEU …

Premature skewing of T cell receptor clonality and delayed memory expansion in HIV-exposed infants

S Dzanibe, AJ Wilk, S Canny, T Ranganath… - Nature …, 2024 - nature.com
While preventing vertical HIV transmission has been very successful, HIV-exposed
uninfected infants (iHEU) experience an elevated risk to infections compared to HIV …

[HTML][HTML] Association of maternal and infant inflammation with neurodevelopment in HIV-exposed uninfected children in a South African birth cohort

T Sevenoaks, CJ Wedderburn, KA Donald… - Brain, Behavior, and …, 2021 - Elsevier
HIV-exposed uninfected (HEU) children may have altered immune regulation and poorer
neurodevelopment outcomes compared to their HIV-unexposed (HU) counterparts …