Unconventional Transformations of Morita–Baylis–Hillman Adducts

A Calcatelli, A Cherubini-Celli, E Carletti… - Synthesis, 2020 - thieme-connect.com
Morita–Baylis–Hillman (MBH) adducts are versatile starting materials widely employed in
Lewis base catalysis. A myriad of different transformations have been reported based on …

Phosphine‐Catalyzed Asymmetric Umpolung Addition of Trifluoromethyl Ketimines to Morita–Baylis–Hillman Carbonates

P Chen, Z Yue, J Zhang, X Lv, L Wang… - Angewandte …, 2016 - Wiley Online Library
A novel phosphine‐catalyzed, highly enantioselective umpolung addition of trifluoromethyl
ketimines to Morita–Baylis–Hillman carbonates was developed and it provides facile access …

Syntheses of lactams by tandem reactions

M Meazza, X Companyó, R Rios - Asian Journal of Organic …, 2018 - Wiley Online Library
Tandem reactions form two or more new bonds, sequentially and in only one step, avoiding
the purification of each step and the use of protecting groups, thus making them greener …

Synthesis of chiral α-trifluoromethylamines with 2, 2, 2-trifluoroethylamine as a “building block”

X Li, J Su, Z Liu, Y Zhu, Z Dong, S Qiu, J Wang… - Organic …, 2016 - ACS Publications
The β-isocupreidine, a cinchonine derived alkaloid, catalyzed asymmetric SN2′–SN2′
reaction between N-2, 2, 2-trifluoroethylisatin ketimines and MBH type carbonates was …

Multifunctional catalysis: stereoselective construction of α-methylidene-γ-lactams via an amidation/Rauhut–Currier sequence

K Kishi, FA Arteaga, S Takizawa, H Sasai - Chemical Communications, 2017 - pubs.rsc.org
Mixing of acryloylchloride, dienone 2, N, N-diisopropylethylamine with chiral organocatalyst
5a, which could simultaneously act as Brønsted and Lewis base catalysts, led to a one-pot …

Stereoelectronic Effect in the Reaction of α-Methylene Lactones with Tertiary Phosphines and Its Application in Organocatalysis

AV Salin, AA Shabanov, KR Khayarov… - The Journal of …, 2023 - ACS Publications
The kinetic data indicate that the addition of tertiary phosphines to α-methylene lactones in
acetic acid is strongly accelerated in comparison to the reactions of related open-chain …

Light-Triggered Catalytic Asymmetric Allylic Benzylation with Photogenerated C-Nucleophiles

S Paria, E Carletti, M Marcon… - The Journal of …, 2020 - ACS Publications
Herein is reported the asymmetric allylic benzylation of Morita–Baylis–Hillman (MBH)
carbonates with 2-methylbenzophenone (MBP) derivatives as nonstabilized photogenerated …

Asymmetric N‐Allylic Alkylation of Hydrazones with Morita–Baylis–Hillman Carbonates

L Yao, CJ Wang - Advanced Synthesis & Catalysis, 2015 - Wiley Online Library
The first asymmetric N‐allylic alkylation of hydrazones with Morita‐Baylis–Hillman (MBH)
carbonates catalyzed by modified Cinchona alkaloids has been developed, affording N …

Synthesis of β-mono-and β, γ-di-substituted α-methylene-γ-lactams

A Hernández-Guadarrama, F Cuevas… - Tetrahedron …, 2022 - Elsevier
A series of β-mono-and β, γ-di-substituted α-methylene-γ-lactams was synthesized. This
method involves the 1, 4-addition of nitroalkanes to arylidenemalonates to obtain nitro …

A [3+ 2]-annulation approach to tetrasubstituted furans from MBH-carbonates of acetylenic aldehydes via sequential substitution/cycloisomerization

CR Reddy, SZ Mohammed… - Organic & Biomolecular …, 2015 - pubs.rsc.org
A novel metal-free approach to construct the tetrasubstituted furans from Morita–Baylis–
Hillman (MBH)-carbonates of acetylenic aldehydes has been developed. This strategy …