Background Most Bantu ethnic groups in southern Africa utilize indigenous herbal
medicines, some of which have psychoactive properties. Traditional medical practitioners …

Ethnopharmacological relevance Sceletium tortuosum (L.) NE Br.(ST) has been used by the
Khoisan people of South Africa as a mood elevator. Its various pharmacological …

A series of novel isobenzofuran-1 (3H)-one derivatives were designed and synthesized as
antidepressants. Firstly, the serotonin reuptake inhibition of these compounds was tested in …

Ethnopharmacology relevance Sceletium tortuosum (L.) NE Br.(ST) is an alkaloid-rich
succulent plant with various mechanisms of action that infer psychotropic effects. These …

Medicinal plants have been used to treat mental health-related conditions among different
ethic groups. Among the commonly used plants in South Africa are Gomphocarpus …

Combretum zeyheri is traditionally used for the treatment of many infections, including
bacterial infections. The aim of this study was to fractionate and evaluate antibacterial …

In South African traditional medicine, Gomphocarpus fruticosus (L.) WT Aiton, Hypoxis
hemerocallidea Fisch. & CA Mey., and Leonotis leonurus.(L.) R. Br. have been recorded …

Depression has long been recognized as a major public health problem. Fear and anxiety
associated with the high morbidity and mortality of COVID-19 have increased risk factors for …

Combretum zeyheri is traditionally used for the treatment of many infections, including
bacterial infections. Te aim of this study was to fractionate and evaluate antibacterial activity …