This review paper describes a new technology, mass cytometry, that addresses applications
typically run by flow cytometer analyzers, but extends the capability to highly multiparametric …

The three subsets of human monocytes, classical, intermediate, and nonclassical, show
phenotypic heterogeneity, particularly in their expression of CD14 and CD16. This has …

Single-cell RNA sequencing has enabled the characterization of highly specific cell types in
many tissues, as well as both primary and stem cell-derived cell lines. An important facet of …

Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis.
We used single-cell “mass cytometry” to examine healthy human bone marrow, measuring …

Fucoidans are sulfated, complex, fucose-rich polymers found in brown seaweeds.
Fucoidans have been shown to have multiple bioactivities, including anti-inflammatory …

Background & Aims Vascular endothelial growth factor (VEGF)− induced angiogenesis is
implicated in fibrogenesis and portal hypertension. However, the function of VEGF in fibrosis …

Virtual patients and digital patients/twins are two similar concepts gaining increasing
attention in health care with goals to accelerate drug development and improve patients' …

Daratumumab is a CD38‐targeted human monoclonal antibody with direct anti‐myeloma
cell mechanisms of action. Flow cytometry in relapsed and/or refractory multiple myeloma …

Background High quality genetic material is an essential pre-requisite when analyzing gene
expression using microarray technology. Peripheral blood mononuclear cells (PBMC) are …

Single cell Raman spectroscopy (SCRS) is a non-invasive and label-free technology,
allowing in vivo and multiple parameter analysis of individual living cells. A single cell …