Current challenges in treatment options for visceral leishmaniasis in India: a public health perspective

O Prakash Singh, B Singh, J Chakravarty… - Infectious diseases of …, 2016 - mednexus.org
Visceral leishmaniasis (VL) is a serious parasitic disease causing considerable mortality
and major disability in the Indian subcontinent. It is most neglected tropical disease …

Amphotericin B formulations and drug targeting

JJ Torrado, R Espada, MP Ballesteros… - Journal of …, 2008 - Elsevier
Amphotericin B is a low-soluble polyene antibiotic which is able to self-aggregate. The
aggregation state can modify its activity and pharmacokinetical characteristics. In spite of its …

Diagnosis and treatment of leishmaniasis: clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical …

N Aronson, BL Herwaldt, M Libman… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that leishmaniasis guidelines cannot always account for individual
variation among patients. They are not intended to supplant physician judgment with respect …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Leishmaniasis: prevention, parasite detection and treatment

T Kobets, I Grekov, M Lipoldova - Current Medicinal Chemistry, 2012 - ingentaconnect.com
Leishmaniasis remains a public health problem worldwide, affecting approximately 12
million people in 88 countries; 50 000 die of it each year. The disease is caused by …

[HTML][HTML] Species-directed therapy for leishmaniasis in returning travellers: a comprehensive guide

CJ Hodiamont, PA Kager, A Bart… - PLoS neglected …, 2014 - journals.plos.org
Background Leishmaniasis is increasingly reported among travellers. Leishmania species
vary in sensitivity to available therapies. Fast and reliable molecular techniques have made …

[HTML][HTML] Structures, targets and recent approaches in anti-leishmanial drug discovery and development

K Seifert - The open medicinal chemistry journal, 2011 - ncbi.nlm.nih.gov
Recent years have seen a significant improvement in available treatment options for
leishmaniasis. Two new drugs, miltefosine and paromomycin, have been registered for the …

Current diagnosis and treatment of visceral leishmaniasis

S Mondal, P Bhattacharya, N Ali - Expert review of anti-infective …, 2010 - Taylor & Francis
Human visceral leishmaniasis (VL), a potentially fatal disease, is most prevalent in the
Indian subcontinent, East Africa and South America. Definite diagnosis and effective …

Visceral leishmaniasis elimination in India: progress and the road ahead

OP Singh, S Sundar - Expert Review of Anti-infective Therapy, 2022 - Taylor & Francis
Introduction As of 2021, visceral leishmaniasis (VL) elimination program has met with
success in reducing the rate of VL to target levels in many locales, but there is persistence of …

[HTML][HTML] Evaluation of apoptotic and antileishmanial activities of Artemisinin on promastigotes and BALB/C mice infected with Leishmania major

F Ghaffarifar, FE Heydari, A Dalimi… - Iranian journal of …, 2015 - ncbi.nlm.nih.gov
Background: In leishmaniasis, some drugs prescribed for treatment have toxic effects and
there are reports about drug resistance in some countries. Due to this fact, using herbal …