The hepatitis B virus (HBV) counts as a major global health problem, as it presents a
significant causative factor for liver-related morbidity and mortality. The development of …

The human hepatitis B virus (HBV), that is causative for more than 240 million cases of
chronic liver inflammation (hepatitis), is an enveloped virus with a partially double-stranded …

Hepatocellular carcinoma (HCC) is one of the most common cancers in the world with an
annual incidence of more than 500 000 in the year 2000. Its incidence is rising in many …

Hepatitis B virus (HBV) is a major cause of liver disease. HBV primarily infects hepatocytes
by a still poorly understood mechanism. After an endocytotic process, the nucleocapsids are …

Here we describe an entirely new class of cell-penetrating peptide (CPP) represented by the
short peptide Xentry (LCLRPVG) derived from an N-terminal region of the X-protein of the …

The expression of a variety of cytoprotective genes is regulated by short cis-acting elements
in their promoters, called antioxidant response elements (AREs). A central regulator of ARE …

Newcomers to the field of biopharmaceuticals require an understanding of the basic
principles and underlying methodology involved in developing protein-and nucleic acid …

Every year, there are about 20 Mio hepatitis E virus (HEV) infections and 60,000 deaths that
are associated with HEV worldwide. At the present, there exists no specific therapy for HEV …

With respect to their genome and their structure, the human hepatitis B virus (HBV) and
hepatitis C virus (HCV) are complete different viruses. However, both viruses can cause an …

Infectious entry of hepatitis B viruses (HBV) has nonconventional facets. Here we analyzed
whether a cell-permeable peptide [translocation motif (TLM)] identified within the surface …