[HTML][HTML] Ferroptosis: a new mechanism of traditional Chinese medicine compounds for treating acute kidney injury

Y Shi, X Shi, M Zhao, M Chang, S Ma… - Biomedicine & …, 2023 - Elsevier
Acute kidney injury (AKI) is a major health concern owing to its high morbidity and mortality
rates, to which there are no drugs or treatment methods, except for renal replacement …

Acute kidney injury and acute respiratory distress syndrome

BD Park, S Faubel - Critical Care Clinics, 2021 - criticalcare.theclinics.com
Acute kidney injury (AKI) is a common complication in patients with acute respiratory distress
syndrome (ARDS) with studies reporting up to 35% incidence rate. The combination of AKI …

Mortality and predictors of acute kidney injury in adults: a hospital-based prospective observational study

A Abebe, K Kumela, M Belay, B Kebede, Y Wobie - Scientific reports, 2021 - nature.com
Acute kidney injury (AKI) is a major global public health problem. It is expensive to manage
and associated with a high rate of prolonged hospitalization and in-hospital mortality. Little is …

An organizational-level program of intervention for AKI: a pragmatic stepped wedge cluster randomized trial

NM Selby, A Casula, L Lamming, J Stoves… - Journal of the …, 2019 - journals.lww.com
Background Variable standards of care may contribute to poor outcomes associated with
AKI. We evaluated whether a multifaceted intervention (AKI e-alerts, an AKI care bundle, and …

Regulator of calcineurin 1 deletion attenuates mitochondrial dysfunction and apoptosis in acute kidney injury through JNK/Mff signaling pathway

JJ Xiao, Q Liu, Y Li, FF Peng, S Wang, Z Zhang… - Cell Death & …, 2022 - nature.com
Abstract Ischemia-reperfusion (I/R) induced acute kidney injury (AKI), characterized by
excessive mitochondrial damage and cell apoptosis, remains a clinical challenge. Recent …

An epidemiologic overview of acute kidney injury in intensive care units

RP Santos, ARS Carvalho, LAB Peres… - Revista da Associação …, 2019 - SciELO Brasil
SUMMARY INTRODUCTION Acute kidney injury (AKI) is a frequent event among critically ill
patients hospitalized in intensive care units (ICU) and represents a global public health …

Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study using the ISARIC–WHO clinical characterisation …

M Wainstein, S MacDonald, D Fryer, K Young… - PLoS …, 2022 - journals.plos.org
Background Acute kidney injury (AKI) is one of the most common and significant problems in
patients with Coronavirus Disease 2019 (COVID-19). However, little is known about the …

Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial

VK Snowdon, NJ Lachlan, AM Hoy, PWF Hadoke… - PLoS …, 2017 - journals.plos.org
Background Chronic liver scarring from any cause leads to cirrhosis, portal hypertension,
and a progressive decline in renal blood flow and renal function. Extreme renal …

[HTML][HTML] Advancements in Trauma-Induced Acute Kidney Injury: Diagnostic and Therapeutic Innovations

S Lassola, F Cundari, G Marini, F Corradi, S De Rosa - Life, 2024 - mdpi.com
Acute kidney injury following trauma impacts patient recovery critically, necessitating an
integrated approach to emergency care and nephrology. This review aims to provide a …

[HTML][HTML] Pan AMPK activation protects tubules in rat ischemic acute kidney injury

H Frikke-Schmidt, K Albarazanji, J Qi… - The Journal of …, 2025 - Elsevier
Acute kidney injury (AKI) is characterized by an abrupt decline in kidney function and has
been associated with excess risks of death, kidney disease progression, and cardiovascular …