[HTML][HTML] The bidirectional relationship between periodontitis and diabetes: new prospects for stem cell-derived exosomes

N Shi, C Kong, L Yuan, L Liu, K Zhao, J Lü… - Biomedicine & …, 2023 - Elsevier
Periodontitis and diabetes have a bidirectional link, making therapeutic treatment of
periodontitis and diabetes challenging. Numerous factors, including microbes, inflammatory …

Disparities and social determinants of periodontal diseases

JM Albandar - Periodontology 2000, 2024 - Wiley Online Library
Periodontal diseases are highly prevalent in populations worldwide and are a major global
public health problem, with major negative impacts on individuals and communities. This …

Aging and oral health: Biological and sociobehavioral perspectives

AP Colombo, B Wu - Journal of dental research, 2023 - journals.sagepub.com
As the life expectancy and growth of the aging population increase globally, efforts to
promote healthy longevity become more important. Holistic policy guidelines and actions …

Cellular senescence in craniofacial tissue regeneration: inducers, biomarkers, and interventions

W Tang, F Huo, J Long, S Zhang… - Tissue Engineering Part B …, 2024 - liebertpub.com
Craniofacial defects and dental tissue loss have significant negative impacts on the structure
and function of jaws and face, often resulting in psychological issues in patients …

Molecular Signatures of Senescence in Periodontitis: Clinical Insights

K Rattanaprukskul, XJ Xia, M Jiang… - Journal of Dental …, 2024 - journals.sagepub.com
Most of the elderly population is afflicted by periodontal diseases, creating a health burden
worldwide. Cellular senescence is one of the hallmarks of aging and associated with several …

[HTML][HTML] Impact of Inflammatory Markers and Senescence-Associated Secretory Phenotype in the Gingival Crevicular Fluid on the Outcomes of Periodontal …

G Baima, F Romano, F Franco, I Roato… - International Journal of …, 2024 - mdpi.com
The aim of this study was to test the molecular expression profile (senescence-associated
secretory phenotype; SASP) in gingival crevicular fluid (GCF) prior to surgery in relation to …

Piezo1 reduces inflammation regulatory ability of periodontal ligament cells to decelerate orthodontic tooth movement in response to heavy mechanical force

L Zheng, Y Zhu, X Meng, Q Zhai, L Xin, H Tan, X He… - 2024 - researchsquare.com
Periodontal ligament (PDL) cells exhibit immunoregulatory characteristics and are being
explored as promising therapeutic candidates for accelerating orthodontic tooth movement …

CSF1R Inhibitor (PLX3397) Alleviates Experimental Periodontitis by Reducing Macrophage Senescence Through the PI3K/AKT/FOXO1 Signaling Pathway

J Kang, J Zhan, Y Wei, T Xiao, L Li, H Fang… - Available at SSRN … - papers.ssrn.com
Background: Macrophage senescence is closely associated with the progression of
periodontitis. While a previous investigation in vitro has demonstrated the potential of …